Clinical utility of histopathology data: cancers of the testis and urinary bladder. Issue 7 (July 2021)

• Record Type: Journal Article
• Authors: Chan, Ronald CK.; Chandra, Ashish; Varma, Murali
• Is Part Of: Diagnostic histopathology. Volume 27:Issue 7(2021)
• Page Start: 290
• Page End: 296
• Publication Date: 2021-07
• Subjects: bladder cancer -- clinical utility -- histopathology -- management -- testicular cancer; Histology, Pathological -- Periodicals; Cytodiagnosis -- Periodicals; Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; Histopathologie -- Périodiques; Pathologie -- Périodiques; Cytodiagnostics -- Périodiques; Diagnostics biologiques -- Périodiques; Histologie -- Technique -- Périodiques; Electronic journals; 616.07582
• DOI: 10.1016/j.mpdhp.2021.04.004
• Languages: English
• ISSNs: 1756-2317

Abstract

Abstract: Histopathology data form the basis of most oncological patient management. Pathology guidelines therefore recommend sets of core data items that should be reported in each specimen. The clinical utility of a particular data item depends on the clinical scenario. Awareness of how these data are used to guide patient management could enable pathologists to focus their resources on clinically important issues. For example, it is generally critical to identify even a minor nonseminomatous component in a predominantly seminomatous testicular germ cell tumour as such patients would be managed as a nonseminoma. However, this finding would be less important in a patient with a raised serum alpha fetoprotein level as such a patient would generally be managed as a nonseminoma even if the histological diagnosis is pure seminoma. In this review, we discuss the clinical utility of various histopathology parameters in the management of bladder and testicular cancer.