How mutations in RYR1 that cause malignant hyperthermia increase RYR1 sensitivity to activators. (July 2021)
- Record Type:
- Journal Article
- Title:
- How mutations in RYR1 that cause malignant hyperthermia increase RYR1 sensitivity to activators. (July 2021)
- Main Title:
- How mutations in RYR1 that cause malignant hyperthermia increase RYR1 sensitivity to activators
- Authors:
- Baker, Matthew L.
Dirksen, Robert T.
Hamilton, Susan L. - Abstract:
- Abstract: New electron cryomicroscopy structures of RYR1 show that mutations associated with Malignant Hyperthermia drive conformational changes in the cytoplasmic domains of the closed channel to more closely resemble those of the open channel.
- Is Part Of:
- Cell calcium. Volume 97(2021)
- Journal:
- Cell calcium
- Issue:
- Volume 97(2021)
- Issue Display:
- Volume 97, Issue 2021 (2021)
- Year:
- 2021
- Volume:
- 97
- Issue:
- 2021
- Issue Sort Value:
- 2021-0097-2021-0000
- Page Start:
- Page End:
- Publication Date:
- 2021-07
- Subjects:
- RYR1 -- Electron cryomicroscopy -- Malignant hyperthermia
Calcium -- Metabolism -- Periodicals
Vertebrates -- Physiology -- Periodicals
Calcium -- Physiological effect -- Periodicals
Cell physiology -- Periodicals
Calcium in the body -- Periodicals
572.516 - Journal URLs:
- http://www.sciencedirect.com/science/journal/01434160 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.ceca.2021.102412 ↗
- Languages:
- English
- ISSNs:
- 0143-4160
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3097.724000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 17431.xml