Scandium calix[n]arenes (n = 4, 6, 8): structural, cytotoxicity and ring opening polymerization studies. Issue 24 (8th June 2021)

• Record Type: Journal Article
• Authors: Alshamrani, Abdullah Fahad A.; Santoro, Orlando; Prior, Timothy J.; Alamri, Mohammed A.; Stasiuk, Graeme J.; Elsegood, Mark R. J.; Redshaw, Carl
• Is Part Of: Dalton transactions. Volume 50:Issue 24(2021)
• Page Start: 8302
• Page End: 8306
• Publication Date: 2021-06-08
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/d1dt01330k
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : Unusual scandium calix[ n ]arenes ( n = 4, 6, 8) have been isolated, structurally characterized and screened for their toxicity and ability to catalyze ring opening polymerizations (ROP) of cyclohexene oxide. Abstract : Interaction of [Sc(OR)3 ] (R = iPr or triflate) with p-tert -butylcalix[ n ]arenes, where n = 4, 6, or 8, affords a number of intriguing structural motifs, which are relatively non-toxic (cytotoxicity evaluated against cell lines HCT116 and HT-29) and a number were capable of the ring opening polymerization (ROP) of cyclohexene oxide.