Horizons of nanotechnology applications in female specific cancers. (February 2021)

• Record Type: Journal Article
• Authors: Rajitha, Balney; Malla, Rama Rao; Vadde, Ramakrishna; Kasa, Prameswari; Prasad, Ganji Lakshmi Vara; Farran, Batoul; Kumari, Seema; Pavitra, Eluri; Kamal, Mohammad Amjad; Raju, Ganji Seeta Rama; Peela, Sujatha; Nagaraju, Ganji Purnachandra
• Is Part Of: Seminars in cancer biology. Volume 69(2021)
• Page Start: 376
• Page End: 390
• Publication Date: 2021-02
• Subjects: ABUS automated breast US -- Ag2S-NP silver sulfide NPs -- AION all-in-one NP -- BC breast cancer -- BTNPs biocompatible piezoelectric barium titanate NPs -- CAs contrast agents -- CC cervical cancer -- CN carbon nanotubes -- CP carboplatin -- CT computed tomography -- DCE dynamic contrast-enhanced -- DISC ductal carcinoma in situ -- EGCG epigallocatechin-gallate -- FDA food and drug administration -- Fe3O4 ferrosoferric oxide -- Gd gadolinium -- GRPR gastrin releasing peptide receptors -- HER2 human epidermal growth factor receptor 2 -- IO-NP iron oxide NPs -- LCP lipid/calcium/phosphate -- MIS minimally invasive surgery -- MRI magnetic resonance imaging -- NAUT NP-assisted ultrasound therapy -- Nbs nanobodies -- NCs nanocarriers -- NIR near infrared -- NP nanoparticle -- NVs nanovehicles -- OC ovarian cancer -- PA photoacoustic -- PCI photochemical internalization -- PET positron emission tomography -- PLA polymeric polylactic acid -- PTX paclitaxel -- QDs quantum dots -- SMA poly(styrene)-co-maleic acid -- SPECT single photon emission computed tomography -- SPION superparamagnetic iron oxide nanoparticles -- SQUID superconducting quantum interference device -- SWBUS screening whole breast ultra sound -- SWBUS screening whole breast US -- Ta4C3 tantalum carbide -- TSNs thermosponge NPs -- US ultrasonography; Female specific cancers -- Breast cancer -- Ovarian cancer -- Cervical cancer -- Nanotechnology; Cancer -- Periodicals; Neoplasms -- Periodicals; Review Literature; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.semcancer.2019.07.005
• Languages: English
• ISSNs: 1044-579X

Abstract

Highlights: Female specific cancers are a major health burden affecting women. Early detection methods and treatment strategies for these cancers are limited. Nanotechnology-based diagnostic tools can improve detection and diagnosis of female cancers. Nanotechnology-based therapeutic strategies can enhance drug delivery and cytotoxicity in female-specific cancers. Abstract: Female-specific cancers are the most common cancers in women worldwide. Early detection methods remain unavailable for most of these cancers, signifying that most of them are diagnosed at later stages. Furthermore, current treatment options for most female-specific cancers are surgery, radiation and chemotherapy. Although important milestones in molecularly targeted approaches have been achieved lately, current therapeutic strategies for female-specific cancers remain limited, ineffective and plagued by the emergence of chemoresistance, which aggravates prognosis. Recently, the application of nanotechnology to the medical field has allowed the development of novel nano-based approaches for the management and treatment of cancers, including female-specific cancers. These approaches promise to improve patient survival rates by reducing side effects, enabling selective delivery of drugs to tumor tissues and enhancing the uptake of therapeutic compounds, thus increasing anti-tumor activity. In this review, we focus on the application of nano-based technologies to the design of novel and innovative diagnostic and therapeutic strategies in the context of female-specific cancers, highlighting their potential uses and limitations.