Green synthesis, characterisation and biological evaluation of plant‐based silver nanoparticles using Quercus semecarpifolia Smith aqueous leaf extract. Issue 1 (24th October 2018)

• Record Type: Journal Article
• Authors: Khattak, Aishma; Ahmad, Bashir; Rauf, Abdur; Bawazeer, Sami; Farooq, Umar; Ali, Jawad; Patel, Seema; Ramadan El‐Sharkawy, Eman; Ikram, Rabia; Linfang, Huang
• Is Part Of: IET nanobiotechnology. Volume 13:Issue 1(2019)
• Page Start: 36
• Page End: 41
• Publication Date: 2018-10-24
• Subjects: scanning electron microscopy -- toxicology -- visible spectra -- particle size -- nanofabrication -- nanomedicine -- transmission electron microscopy -- silver -- ultraviolet spectra -- differential thermal analysis -- nanoparticles -- X‐ray diffraction -- botany -- biochemistry -- cellular biophysics; green synthesis -- biological evaluation -- plant‐based silver nanoparticles -- reliable methods -- metallic nanoparticles -- eco‐friendly cost‐effective protocol -- silver NPs -- ultraviolet–visible spectroscopic analysis -- highest absorbance peak -- particle size -- structure -- transmission electron microscopy analysis -- TEM imaging -- crystalline nature -- X‐ray powder diffraction patterns -- differential thermal analysis -- pharmacological evaluation -- aqueous extracts -- good cytotoxic activity -- significant antioxidant activity -- AgNPs exhibited good phytotoxic potential -- bio‐inspired synthesis -- Quercus semecarpifolia Smith aqueous leaf extract -- scanning electron microscopy -- thermogravimetry -- crude methanolic -- n‐hexane -- chloroform -- ethyl acetate -- phytotoxic potential -- haemagglutination activity -- size 20.0 nm to 50.0 nm -- wavelength 430.0 nm -- temperature 100 degC to 1000 degC -- Ag; Biotechnology -- Periodicals; Nanotechnology -- Periodicals; 660.6
• DOI: 10.1049/iet-nbt.2018.5063
• Languages: English
• ISSNs: 1751-8741

Abstract

Abstract : The development of reliable and green methods for the fabrication of metallic nanoparticles (NPs) has many advantages in the field of nanotechnology. In this direction, the present work describes an eco‐friendly and cost‐effective protocol for the production of silver NPs (AgNPs) using an aqueous extract of Quercus semecarpifolia leaves. Different techniques were carried out for the characterisation of the synthesised AgNPs. The ultraviolet–visible spectroscopic analysis showed the highest absorbance peak at 430 nm. The particle size and structure were confirmed by scanning electron microscopy as well as transmission electron microscopy (TEM) analysis. From TEM imaging, it was revealed that the formed particles were spherical with an average size of 20–50 nm. The crystalline nature of the NPs was determined by X‐ray powder diffraction patterns. Thermogravimetry and differential thermal analysis were also evaluated by a temperature increment from 100 to 1000°C. Bio‐inspired synthesis of AgNPs was performed for their pharmacological evaluation in relation to the activities of the crude methanolic, n ‐hexane, chloroform, ethyl acetate, and aqueous extracts. Good cytotoxic activity was exhibited by the green‐synthesised AgNPs (77%). Furthermore, the AgNPs were found to exhibit significant antioxidant activity at 300 μg/ml (82%). The AgNPs also exhibited good phytotoxic potential (75%).