Initiation and regulation of the heartbeat. Issue 4 (April 2021)

• Record Type: Journal Article
• Authors: Kirkman, Emrys
• Is Part Of: Anaesthesia and intensive care medicine. Volume 22:Issue 4(2021)
• Page Start: 259
• Page End: 262
• Publication Date: 2021-04
• Subjects: Action potential -- pacemaker cells -- sinoatrial node; Anesthesiology -- Periodicals; Critical care medicine -- Periodicals; Anesthesia -- Periodicals; Intensive care -- Periodicals; Electronic journals; Periodicals; 617.9605
• DOI: 10.1016/j.mpaic.2021.02.008
• Languages: English
• ISSNs: 1472-0299

Abstract

Abstract: The heart has all the components necessary to initiate and maintain a regular heartbeat, without the need for external influence. Thus, a transplanted heart without nervous connection, or a heart completely removed from the body, if adequately perfused with oxygen, beats rhythmically. In the normal intact body, the function of the nervous and humoral regulation is to modulate the activity of the heart, though some aspects of modulation are intrinsic properties of cardiac muscle.