Orbital Adult T-Cell Leukemia/lymphoma With Skin Involvement Demonstrated on FDG PET/CT. (December 2019)

• Record Type: Journal Article
• Authors: Hotta, Masatoshi; Minamimoto, Ryogo
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 12(2019)
• Publication Date: 2019-12
• Subjects: ATLL -- FDG -- orbit -- PET -- T-cell lymphoma; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002773
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: An 85-year-old woman presented with decreased visual acuity. MRI of the brain revealed bilateral orbital masses, and FDG-PET/CT demonstrated moderate to intense uptake in the orbital tumors and thickened skin on the left lower leg. Biopsies of the orbital and cutaneous lesions revealed infiltration by T-cell lymphoma, and the presence of human T-cell lymphotropic virus type 1 antigens confirmed the diagnosis of adult T-cell leukemia/lymphoma (ATLL). Although orbital ATLL is rare, the skin is a common site of extranodal involvement of T-cell lymphomas, including ATLL, and FDG uptake by a cutaneous lesion can facilitate early diagnosis.