T2 mapping of the acetabular cartilage in infants and children with developmental dysplasia of the hip. (October 2021)

• Record Type: Journal Article
• Authors: Lu, Zhao; Pan, Shinong; Wang, Baijun; Liu, Jiahui; Gao, Tianyang; Lyu, Xiaohong
• Is Part Of: Acta radiologica. Volume 62:Number 10(2021)
• Page Start: 1418
• Page End: 1425
• Publication Date: 2021-10
• Subjects: Magnetic resonance imaging -- acetabulum -- hip dislocation -- T2 mapping; Radiology, Medical -- Periodicals; Radiography, Medical -- Periodicals; Radiotherapy -- Periodicals; 616.0757
• DOI: 10.1177/0284185120966684
• Languages: English
• ISSNs: 0284-1851

Abstract

Background: T2 mapping is useful for evaluating the cartilage matrix. Purpose: To determine the variations in the acetabular cartilage T2 relaxation values between healthy individuals and those with developmental dysplasia of the hip (DDH). Material and Methods: Thirty-three patients with unilateral DDH underwent 3-T magnetic resonance imaging (MRI) between January 2018 and February 2019. Fifteen volunteers (30 hips) were enrolled as controls. T2 values were measured with the T2 mapping sequence in all layers and were equally divided into three layers (deep, middle, and superficial) with equal thickness. We calculated the mean T2 relaxation values for the full thickness, deep, middle, and superficial layers and compared the values between the different groups. In addition, the inter- and intra-observer agreements were calculated. Results: The T2 relaxation values in the DDH arm were significantly lower in the middle, superficial, and full thickness layers compared with those of the volunteers and contralateral hips. The T2 relaxation values of the deep layers showed no significant difference between the different groups. The acetabular cartilage T2 relaxation values increased from the deep layer to the superficial layer in the control and contralateral groups. Both inter- and intra-observer agreements were good. Conclusion: MRI T2 mapping may help to diagnose developmental disorders of the acetabular cartilage matrix in infants and children with DDH. Abnormal acetabular cartilage T2 relaxation values may be due to the extraordinary stress load of the femoral head.