Orbital Epstein‐Barr virus‐related post‐transplant lymphoproliferative disorder in a 13‐year‐old girl with cord blood transplantation. Issue 3 (18th December 2020)

• Record Type: Journal Article
• Authors: Shigemura, Tomonari; Maruyama, Yuta; Shigeto, Shohei; Nakazawa, Yozo; Kanno, Hiroyuki
• Is Part Of: Transplant infectious disease. Volume 23:Issue 3(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-12-18
• Subjects: cord blood transplantation -- Epstein‐Barr virus -- orbital PTLD -- post‐transplant lymphoproliferative disorder; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.13536
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Epstein‐Barr virus‐associated post‐transplant lymphoproliferative disorder (EBV‐PTLD) is increasingly recognized as a life‐threatening complication after transplantation. Most areas affected by EBV‐PTLD are lymph nodes, with occasional reports of extranodal lesions such as the gastrointestinal tract and central nervous system; however, orbital regions are extremely rare. We report a case of EBV‐PTLD in a cord blood transplant recipient with a tumor in the upper right eyelid. Ultimately, eye symptoms were the first signs of PTLD. Transplant physicians should consider the possibility of PTLD when encountering an orbital lesion.