Hollow Microneedle Arrays Produced by Low‐Cost, High‐Fidelity Replication of Hypodermic Needle Tips for High‐Dose Transdermal Drug Delivery. Issue 6 (24th June 2021)

• Record Type: Journal Article
• Authors: Zhou, Cuiping; Tang, Hao; Zhang, Li; An, Hong; Wu, Yunjin; Tang, Ding; Zhou, Jianhua
• Is Part Of: Advanced engineering materials. Volume 23:Issue 6(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-06-24
• Subjects: Materials -- Periodicals; 620.11
• DOI: 10.1002/adem.202170020
• Languages: English
• ISSNs: 1438-1656

Abstract

Abstract : Hollow microneedle arrays (HMN), which exhibit advantages like safety in use, painlessness, high drug loading, precise administration and convenience of connecting to external devices, have been massively produced via a simple, low‐cost and high‐fidelity replication strategy. The as‐obtained HMN could be integrated onto a microfluidic chip with different microchannels, and the microfluidic chip could be further applied to fabricate a bundle device by attaching the chip to a looped zip tie. By using this zip tie, vaccines or drugs could be loaded in a convenient way, as described in the article, number 2001355, by Jianhua Zhou and co‐workers.