A self-assembled DNA nanostructure as a FRET nanoflare for intracellular ATP imaging. Issue 51 (1st June 2021)

• Record Type: Journal Article
• Authors: Cai, Shijun; Wang, Jiaoli; Li, Jing; Zhou, Bing; He, Chunmei; Meng, Xiangxian; Huang, Jin; Wang, Kemin
• Is Part Of: Chemical communications. Volume 57:Issue 51(2021)
• Page Start: 6257
• Page End: 6260
• Publication Date: 2021-06-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc02316k
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A novel self-assembled DNA nanostructure was designed as a FRET nanoflare for ATP imaging in live cells. Abstract : Due to the incorporation of gold nanoparticles (AuNPs), previously reported AuNP-based FRET nanoflares still have some problems, such as non-negligible cytotoxicity and a time-consuming preparation procedure. In this communication, a novel AuNP-free FRET nanoflare for intracellular ATP imaging is developed based on a DNA nanostructure, which is self-assembled through cyclic U-type hybridization only involving a certain number of DNA strands.