Dual sensing of methionine and aspartic acid in aqueous medium by a quinoline-based fluorescent probe. Issue 25 (7th June 2021)

• Record Type: Journal Article
• Authors: Elamathi, C.; Butcher, R. J.; Mohankumar, A.; Sundararaj, P.; Elango, K. P.; Kalaivani, P.; Prabhakaran, R.
• Is Part Of: Dalton transactions. Volume 50:Issue 25(2021)
• Page Start: 8820
• Page End: 8830
• Publication Date: 2021-06-07
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/d1dt00648g
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : A quinoline-based Schiff base sensor (6MPS ) has been developed for the selective sensing of methionine and aspartic acid in aqueous medium in both in vitro and in vivo live cells through "on–off–on" type selective detection of copper ion. Abstract : A quinoline-based Schiff base sensor, 6-methyl-2-oxo-1, 2-dihydro-quinoline-3-carboxaldehyde-4( N )-phenylsemicarbazone (6MPS ), has been developed for selective sensing of methionine and aspartic acid in aqueous medium through "on–off–on" type selective detection of copper ion. Fluorescence imaging of 6MPS, 6MPSC, 6MPSCN, 6MPSC-met, 6MPSCN-met, 6MPSC-asp and 6MPSCN-asp has been successfully demonstrated, in which the sensing probes 6MPSC-met, 6MPSCN-met, 6MPSC-asp and 6MPSCN-asp displayed bright green fluorescence in both in vitro and in vivo live cells.