P1 gene of Mycoplasma pneumoniae isolated from 2016 to 2019 and relationship between genotyping and macrolide resistance in Hokkaido, Japan. Issue 6 (24th June 2021)

• Record Type: Journal Article
• Authors: Ishiguro, Nobuhisa; Sato, Rikako; Kikuta, Hideaki; Nakanishi, Masanori; Aoyagi, Hayato; Mori, Toshihiko; Nagano, Naoko; Tabata, Yuichi; Hazama, Kyosuke; Konno, Mutsuko; Yamanaka, Tatsuru; Azuma, Katsumi; Tanaka, Hiroshi; Narita, Mitsuo; Morita, Keisuke; Odagawa, Yasuhisa; Ishizaka, Akihito; Tsuchida, Akira; Sasaki, Satoshi; Horino, Atsuko; Kenri, Tsuyoshi; Togashi, Takehiro; Manabe, Atsushi
• Is Part Of: Journal of medical microbiology. Volume 70:Issue 6(2021)
• Publication Date: 2021-06-24
• Subjects: Mycoplasma pneumoniae -- macrolides -- antibiotic resistance -- Japan; Medical microbiology -- Periodicals; 616.9041
• DOI: 10.1099/jmm.0.001365
• Languages: English
• ISSNs: 0022-2615

Abstract

Abstract : We characterized 515 Mycoplasma pneumoniae specimens in Hokkaido. In 2013 and 2014, the p1 gene type 1 strain, mostly macrolide-resistant, was dominant and the prevalence of macrolide resistance was over 50 %. After 2017, the p1 gene type 2 lineage, mostly macrolide-sensitive, increased and the prevalence of macrolide resistance became 31.0 % in 2017, 5.3 % in 2018 and 16.3 % in 2019.