Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy. (July 2021)

• Record Type: Journal Article
• Authors: Forghani, Farnoush; Patton, Taylor; Kwak, Jennifer; Thomas, David; Diot, Quentin; Rusthoven, Chad; Castillo, Richard; Castillo, Edward; Grills, Inga; Guerrero, Thomas; Miften, Moyed; Vinogradskiy, Yevgeniy
• Is Part Of: Radiotherapy and oncology. Volume 160(2021)
• Page Start: 120
• Page End: 124
• Publication Date: 2021-07
• Subjects: SPECT ventilation/perfusion -- Functional avoidance -- Lung cancer -- Spearman correlation -- Dice Similarity -- 4DCT scans; Oncology -- Periodicals; Radiotherapy -- Periodicals; Tumors -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiothérapie -- Périodiques; Cancérologie -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9940642
• DOI: 10.1016/j.radonc.2021.04.022
• Languages: English
• ISSNs: 0167-8140

Abstract

Abstract: This study investigates agreement between ventilation and perfusion for lung cancer patients undergoing radiotherapy. Ventilation-perfusion scans of nineteen patients with stage III lung cancer from a prospective protocol were compared using voxel-wise Spearman correlation-coefficients. The presented results show in about 25% of patients, ventilation and perfusion exhibit lower agreement.