Atrial cardiopathy in embolic stroke of undetermined source. Issue 6 (4th May 2021)
- Record Type:
- Journal Article
- Title:
- Atrial cardiopathy in embolic stroke of undetermined source. Issue 6 (4th May 2021)
- Main Title:
- Atrial cardiopathy in embolic stroke of undetermined source
- Authors:
- Chen, Jing
Gao, Fenglian
Liu, Wenhong - Abstract:
- Abstract: Introduction: Atrial cardiopathy is one of the most common potential sources of thromboembolism for embolic stroke of undetermined source (ESUS). The study aims to investigate the incidence of atrial cardiopathy (defined by severe left atrial enlargement (sLAE) or elevated serum N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) > 250 pg/ml) in patients with ESUS and compare with other stroke subtypes. Methods: We retrospectively collected data of 936 consecutive patients with diffusion‐weighted imaging‐confirmed acute ischemic stroke. The incidence of atrial cardiopathy was examined in ESUS, large artery atherosclerosis (LAA), and small vessel disease (SVD) strokes. Clinical characteristics were compared between ESUS patients with atrial cardiopathy (AC‐ESUS) and patients with atrial fibrillation‐induced cardioembolism (AF‐CE) stroke. Results: 245 patients were diagnosed with ESUS, while others were diagnosed with LAA ( n = 312), SVD ( n = 258), and AF‐CE ( n = 121) strokes. The incidence of sLAE in ESUS patients was higher than in LAA or SVD group (5.3% vs. 1.6% and 1.2%, respectively, p = .005) and higher than in combined LAA/SVD group (5.3% vs. 1.4%, p = .001). The incidence of elevated serum NT‐proBNP in ESUS patients was not statistically different from that in LAA or SVD group. Compared with patients with AF‐CE stroke, AC‐ESUS patients had milder manifestations, had less hemorrhagic transformation, had better short‐term outcome, and had fewerAbstract: Introduction: Atrial cardiopathy is one of the most common potential sources of thromboembolism for embolic stroke of undetermined source (ESUS). The study aims to investigate the incidence of atrial cardiopathy (defined by severe left atrial enlargement (sLAE) or elevated serum N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) > 250 pg/ml) in patients with ESUS and compare with other stroke subtypes. Methods: We retrospectively collected data of 936 consecutive patients with diffusion‐weighted imaging‐confirmed acute ischemic stroke. The incidence of atrial cardiopathy was examined in ESUS, large artery atherosclerosis (LAA), and small vessel disease (SVD) strokes. Clinical characteristics were compared between ESUS patients with atrial cardiopathy (AC‐ESUS) and patients with atrial fibrillation‐induced cardioembolism (AF‐CE) stroke. Results: 245 patients were diagnosed with ESUS, while others were diagnosed with LAA ( n = 312), SVD ( n = 258), and AF‐CE ( n = 121) strokes. The incidence of sLAE in ESUS patients was higher than in LAA or SVD group (5.3% vs. 1.6% and 1.2%, respectively, p = .005) and higher than in combined LAA/SVD group (5.3% vs. 1.4%, p = .001). The incidence of elevated serum NT‐proBNP in ESUS patients was not statistically different from that in LAA or SVD group. Compared with patients with AF‐CE stroke, AC‐ESUS patients had milder manifestations, had less hemorrhagic transformation, had better short‐term outcome, and had fewer in‐hospital complications. Conclusions: The incidence of sLAE was higher in ESUS patients than in patients with noncardioembolic strokes. AC‐ESUS was milder when compared to AF‐CE stroke. Abstract : The incidence of severe left atrial enlargement is higher in ESUS patients than in patients with noncardioembolic stroke, while there was no difference in the proportion of elevated serum NT‐proBNP between them. ESUS with atrial cardiopathy was a milder form when compared to stroke caused by atrial fibrillation‐induced cardioembolism. … (more)
- Is Part Of:
- Brain and behavior. Volume 11:Issue 6(2021)
- Journal:
- Brain and behavior
- Issue:
- Volume 11:Issue 6(2021)
- Issue Display:
- Volume 11, Issue 6 (2021)
- Year:
- 2021
- Volume:
- 11
- Issue:
- 6
- Issue Sort Value:
- 2021-0011-0006-0000
- Page Start:
- n/a
- Page End:
- n/a
- Publication Date:
- 2021-05-04
- Subjects:
- atrial cardiopathy -- embolic stroke of undetermined source -- N‐terminal pro‐B‐type natriuretic peptide -- severe left atrial enlargement
Neurology -- Periodicals
Neurosciences -- Periodicals
Psychology -- Periodicals
Psychiatry -- Periodicals
616.8005 - Journal URLs:
- http://bibpurl.oclc.org/web/52745 \u http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2157-9032 ↗
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2157-9032 ↗
http://www.ncbi.nlm.nih.gov/pmc/journals/1650 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/brb3.2160 ↗
- Languages:
- English
- ISSNs:
- 2162-3279
- Deposit Type:
- Legaldeposit
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- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 17327.xml