CADASIL presenting as late‐onset mania with anosognosia. Issue 1 (8th December 2019)

• Record Type: Journal Article
• Authors: Uppal, Manik; Kanellopoulos, Dora; Kotbi, Nabil
• Is Part Of: Clinical case reports. Volume 8:Issue 1(2020)
• Page Start: 47
• Page End: 50
• Publication Date: 2019-12-08
• Subjects: anosognosia -- bipolar disorder -- CADASIL -- personality change; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.2594
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late‐onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges to recognition and appropriate management of CADASIL in susceptible patients. Abstract : The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late‐onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges to recognition and appropriate management of CADASIL in susceptible patients.