Evaluation of appendicitis risk prediction models in adults with suspected appendicitis. Issue 1 (3rd December 2019)

• Record Type: Journal Article
• Authors: Bhangu, A.
• Other Names: Nepogodiev D investigator.; Matthews JH investigator.; Morley GL investigator.; Naumann DN investigator.; Ball A investigator.; Chauhan P investigator.; Bhanderi S investigator.; Mohamed I investigator.; Glasbey JC investigator.; Wilkin RJW investigator.; Drake TM investigator.; Clements J investigator.; Blencowe NS investigator.; Herrod PJJ investigator.; Pata F investigator.; Frasson M investigator.; Blanco‐Colino R investigator.; Soares AS investigator.; Bhangu A investigator.; Nepogodiev D investigator.; Bhangu A investigator.; Matthews JH investigator.; Morley GL investigator.; Bhanderi S investigator.; Ball A investigator.; Chauhan P investigator.; Jain S investigator.; Mohamed I investigator.; Amuthalingam T investigator.; Tyler R investigator.; Glasbey JC investigator.; Wilkin RJW investigator.; Pata F investigator.; Frasson M investigator.; Blanco‐Colino R investigator.; Soares AS investigator.; Bhangu A investigator.; Nepogodiev D investigator.; Griffiths EA investigator.; Pinkney TD investigator.; Gee O investigator.; Morton DG investigator.; Beggs A investigator.; Beral D investigator.; Bhangu A investigator.; Blencowe NS investigator.; Bowley D investigator.; Cruickshank N investigator.; Daniels I investigator.; Griffiths E investigator.; Hornby ST investigator.; Lund JN investigator.; Marriott P investigator.; Pinkney TD investigator.; Singh P investigator.; Smart NJ investigator.; Speake D investigator.; Thompson C investigator.; Torkington J investigator.; Torrance A investigator.; Vohra R investigator.; Warren O investigator.; Wilkin RJW investigator.; Winter DC investigator.; Pata F investigator.; Pellino G investigator.; Sgrò A investigator.; Simioni A investigator.; Farina V investigator.; Podda M investigator.; Di Saverio S investigator.; Birindelli A investigator.; Pasquali S investigator.; ITSurg investigator.; Soares AS investigator.; Surg PT investigator.; Blanco‐Colino R investigator.; Frasson M investigator.; Blencowe NS investigator.; Bolton W investigator.; Bradshaw CJ investigator.; Chean CS investigator.; Harris G investigator.; Haddow JB investigator.; Jamieson NB investigator.; McCain S investigator.; Mason J investigator.; Milgrom D investigator.; Nana GR investigator.; Mohamed MS Noor investigator.; Brien JO investigator.; Pearce JCH investigator.; Rabie M investigator.; Sahnan K investigator.; Sarmah P investigator.; Skerritt C investigator.; Ghazanfar MA investigator.; Sreedharan L investigator.; Kabwama S investigator.; Gray RT investigator.; Kamande IW investigator.; Nazarian S investigator.; Dar FA investigator.; Misky AT investigator.; Arunachalam S investigator.; Twum‐Barima CS investigator.; Mohamed IM investigator.; Connor KL investigator.; Coe PO investigator.; Kosti A investigator.; Elshaer M investigator.; Colvin DA investigator.; Charalambous MP investigator.; Yeung KTD investigator.; Merker LAG investigator.; Morrison TEM investigator.; Thaventhiran AJ investigator.; Gilbert TM investigator.; Clements JM investigator.; Hicks G investigator.; Afshar S investigator.; Mckinley NC investigator.; Assaf N investigator.; Hanna T investigator.; Macinnes EGE investigator.; Thavanesan N investigator.; Dubois AS investigator.; Palani‐Velu LK investigator.; Tezas S investigator.; Yow LPS investigator.; Radwan RW investigator.; Jamieson NB investigator.; Abdelrahman M investigator.; Lee KA investigator.; Zarka Z A investigator.; Mcdowall NA investigator.; Tan CY investigator.; Venn ML investigator.; Ashmore DL investigator.; Whitehorn SE investigator.; Golder AM investigator.; Reddy A investigator.; Delimpalta C investigator.; Kay OH investigator.; Sarmah P investigator.; Shah SM investigator.; Eiben I investigator.; Doyle C investigator.; Tudyka V investigator.; Issa E investigator.; West H investigator.; Brewer HK investigator.; Farrow EZ investigator.; Taylor NS investigator.; Smart CJ investigator.; Griffiths NP investigator.; Halkias C investigator.; Vitish‐Sharma P investigator.; Knight SR investigator.; Mowbray NG investigator.; Olivier JB investigator.; Lee KJ investigator.; Clement KD investigator.; Chrastek DRR investigator.; Panda N investigator.; Connor MJ investigator.; Fahmy SE investigator.; Bryan ES investigator.; Ngu WS investigator.; Adegbola SO investigator.; Vaughan EM investigator.; Stupalkowska W investigator.; Simmonds LFC investigator.; Malik A investigator.; Hussein A investigator.; Karim MJ investigator.; Singhal T investigator.; Ormiston R investigator.; Nepogodiev D investigator.; Kung VWS investigator.; Rabie MA investigator.; Park JH investigator.; Lal N investigator.; Worku D investigator.; D'Auria M investigator.; Ang A investigator.; Orizu M investigator.; Gammeri E investigator.; Clough ECS investigator.; Choy CH investigator.; Herrod PJJ investigator.; Lawday S investigator.; Hann AJ investigator.; Robinson D investigator.; Wardle BG investigator.; Mcdonnell D investigator.; Rutherford DG investigator.; Hickey LM investigator.; Garg AG investigator.; Rezvani S investigator.; Bell CR investigator.; Mahmood F investigator.; Rehman S investigator.; Donaldson G investigator.; Peleki A investigator.; Pearce L investigator.; Sharp OL investigator.; Jain S investigator.; Singh S investigator.; Thompson DB investigator.; El‐Tayar O investigator.; Hollyman M investigator.; Rupasinghe SN investigator.; Toomey DB investigator.; Murray MP investigator.; Amtul N investigator.; Mersh RJ investigator.; Newton RC investigator.; Al‐Khyatt W investigator.; Stephens GF investigator.; Abbas SH investigator.; Iqbal MR investigator.; Brown CE investigator.; Renshaw S investigator.; Hureibi KA investigator.; Pullabatla‐Venkata UP investigator.; Donohoe N O investigator.; Myatt A investigator.; Egan RJ investigator.; Rangarajan K investigator.; Trail M investigator.; Mckay SC investigator.; Engall NFT investigator.; Jerome E investigator.; Townsend DC investigator.; Patel BY investigator.; Pronin S investigator.; Chandratreya N investigator.; Choong JH investigator.; Mohamed TM investigator.; Hudson‐Peacock NJ investigator.; Manson R investigator.; Bhanderi S investigator.; Hebbar KRM investigator.; Mothe BS investigator.; Weegenaar CR investigator.; Saad M investigator.; Bowman CR investigator.; Serventi F investigator.; Fleres F investigator.; Foppa C investigator.; Pata G investigator.; Baronio G investigator.; Pertile D investigator.; Lucchi A investigator.; Sagnotta A investigator.; Maretto I investigator.; Campagnaro T investigator.; Gatti M investigator.; Gjoni EGJ investigator.; Roscio F investigator.; Inama M investigator.; Coccolini F investigator.; Sgrò A investigator.; Colombo F investigator.; Avanzolini A investigator.; Aresu S investigator.; De‐Manzoni‐Garberini A investigator.; Merlini DA investigator.; Chessa A investigator.; Tamini N investigator.; Mulas S investigator.; Cillara N investigator.; Coletta D investigator.; Atzeni J investigator.; Erdas E investigator.; Gallo G investigator.; Francone E investigator.; Di Gioia P investigator.; Birindelli A investigator.; Bianchi CL investigator.; Ferrara F investigator.; Biancafarina A investigator.; Podda M investigator.; Scabini S investigator.; Marano L investigator.; Miegge A investigator.; Sasia D investigator.; Savino G investigator.; Pata F investigator.; Scatizzi M investigator.; D'Amico FE investigator.; Arcuri GA investigator.; Gavagna L investigator.; Salamone G investigator.; Tatulli F investigator.; Goldin E investigator.; Matos ML investigator.; Caldeira AB investigator.; Romano J investigator.; Pereira J investigator.; Azevedo JGM investigator.; Azevedo JM investigator.; Simoes JFF investigator.; Silva ACQ investigator.; Soares AS investigator.; O'Leary DP investigator.; Kennedy ND investigator.; Quinn EM investigator.; Zhang AY investigator.; Neary PM investigator.; De‐Marchi JA investigator.; O'Connor BR investigator.; Wijesundera K investigator.; Foley NM investigator.; Wong J investigator.; Kennedy ND investigator.; Tiedt LA investigator.; Bolger JC investigator.; Connelly TM investigator.; Ahmed OS investigator.; Vigorita V investigator.; García V investigator.; Arredondo J investigator.; Redondo E investigator.; Sainz B investigator.; Aldrey I investigator.; Landaluce‐Olavarria A investigator.; Gómez A De Andrés investigator.; Cordoba E investigator.; Sánchez‐Fuentes MN investigator.; Cerdán‐Santacruz C investigator.; Beltran‐De‐Heredia J investigator.; García MTGM investigator.; Veres T investigator.; García‐Novoa A investigator.; Abellán A Melero investigator.; García‐Catalá L investigator.; Ruiz‐Marín M investigator.; Menendez P investigator.; Roldán‐Ortiz S investigator.; Navas‐Cuéllar JA investigator.; Sabia D investigator.; Gomez‐Rosado JC investigator.; Navidad M Serrano investigator.; Caula C investigator.; Sanchez ER investigator.; Espin‐Basany E investigator.; Fernández‐Martínez D investigator.; Bravo‐Gutiérrez AF investigator.; Payá‐Llorente C investigator.; Dujovne P investigator.; Lima F investigator.; Soria‐Aledo V investigator.; Gomez CJ investigator.; Pascual‐Miguelañez I investigator.; Muinelo M investigator.; Alvarez C Magadan investigator.; Vargas‐Pierola HJ investigator.; Vallve‐Bernal M investigator.; Hidalgo‐Rosas JM investigator.; Arenal‐Vera JJ investigator.; Sena‐Ruiz F investigator.; Sanchez‐Guillen L investigator.; Villarejo‐Campos P investigator.; Tallon‐Aguilar L investigator.; Garcea A investigator.; Bennett JM investigator.; Whittaker L investigator.; Gidwani AL investigator.; Byrnes CK investigator.; Saunders SMF investigator.; Shiwani MH investigator.; Ashraf N investigator.; Venkatasubramaniam AK investigator.; Bevan KE investigator.; Mcarthur D investigator.; Mustafa AK investigator.; Griffith JP investigator.; Blazeby JM investigator.; Charalabopoulos A investigator.; Campbell W investigator.; Reese G investigator.; Warren OJ investigator.; Peacock M investigator.; Menzies D investigator.; Jenner D investigator.; Eardley NJ investigator.; Yoong S investigator.; Abulafi M investigator.; Avalapati H investigator.; Thompson R investigator.; Nastro P investigator.; Kochupapy R investigator.; Beral D investigator.; Stubbs BM investigator.; McIntyre R investigator.; Crozier J investigator.; Patel PK investigator.; Pento V investigator.; Beasley WD investigator.; Roxburgh CSD investigator.; Hornby ST investigator.; Youssef H investigator.; Alexander R investigator.; Denley S investigator.; Di Franco F investigator.; Quddus A investigator.; Saha A investigator.; Hunter I investigator.; Hannay JAF investigator.; Reddy A investigator.; Velchuru VR investigator.; Bond‐Smith GEL investigator.; Salama Y investigator.; Bhargava A investigator.; Panagiotopoulos SP investigator.; Watson N investigator.; Tudyka V investigator.; Garcea G investigator.; Boddy AP investigator.; Dunning PG investigator.; Lloyd Geraint investigator.; Gurjar SV investigator.; Smart CJ investigator.; Hill J investigator.; Andrews B investigator.; Singh A investigator.; Ruzvidzo F investigator.; Shingler G investigator.; Mahon D investigator.; Elgaddal S investigator.; Payne CJ investigator.; Shaikh IA investigator.; Dalmia S investigator.; Nair MS investigator.; Finch JG investigator.; Chapple KS investigator.; Bawa S investigator.; Watfah J investigator.; Carden CA investigator.; Makhija R investigator.; Rao M investigator.; Sarveswaran J investigator.; Vijay V investigator.; Rekhraj S investigator.; Singhal T investigator.; Knight B investigator.; Pinkney TD investigator.; Siddiqui MN investigator.; Sebastian JF investigator.; Glen P investigator.; Vakis S investigator.; Ebied H investigator.; Vohra R investigator.; Rajaram R investigator.; Gray J investigator.; Mcgrath D investigator.; Faulkner G investigator.; Gopalswamy S investigator.; Lund JN investigator.; Smart NJ investigator.; Varcada M investigator.; Woodward A investigator.; Williams GL investigator.; Szentpali K investigator.; Ravindran R investigator.; Bronder C investigator.; Thaha MA investigator.; Rate A investigator.; Shetty V Daya investigator.; Rao VSR investigator.; Sajid MS investigator.; Clements B investigator.; Patel RT investigator.; Mason C investigator.; Branagan G investigator.; Torrance A investigator.; Maude K investigator.; Kaur G investigator.; Lyons A investigator.; Ainsworth P investigator.; Hagger R investigator.; Zadi AZ investigator.; Maslekar SU investigator.; Kinross J investigator.; Irukulla S investigator.; Hawkins W investigator.; Wheatstone S investigator.; Magro T investigator.; Bailey STR investigator.; Marshall G investigator.; Mccullough J investigator.; Marangoni G investigator.; Leung EL investigator.; Borg CM investigator.; Gopinath S investigator.; Torkington J investigator.; Kirkby‐Bott J investigator.; Yalamarthi S investigator.; Mirza S investigator.; Brett M investigator.; Ramcharan S investigator.; Pandey V investigator.; Thava B investigator.; Speake D investigator.; Chandratreya N investigator.; Andreani SM investigator.; Sahay SJ investigator.; Aravind B investigator.; Downey M investigator.; Nicol D investigator.; Whitehouse P investigator.; Sharma A investigator.; Francis N investigator.; Chitsabesan P investigator.; Stewart DJ investigator.; Norcia GG investigator.; Cucinotta E investigator.; Cianchi F investigator.; Romario U Fumagalli investigator.; Taglietti L investigator.; Capelli P investigator.; Garulli G investigator.; Parisi A investigator.; Nitti D investigator.; Guglielmi A investigator.; Alonzo A investigator.; Scandroglio IS investigator.; Roscio F investigator.; Moretto G investigator.; Ansaloni L investigator.; Pietrabissa A investigator.; Foschi D investigator.; Vettoretto N investigator.; Ercolani G investigator.; Coppola M investigator.; Colangelo E investigator.; Morandi E investigator.; Chessa A investigator.; Tamini N investigator.; Niolu P investigator.; Pala M investigator.; Coletti M investigator.; Pisanu A investigator.; Nicolosi A investigator.; Sammarco G investigator.; Berti S investigator.; Soliani P investigator.; Tonini V investigator.; Bianchi CL investigator.; Stella M investigator.; Ceccarelli G investigator.; De Nisco C investigator.; Scabini S investigator.; Castagnoli G investigator.; De Nardi P investigator.; Borghi F investigator.; Agresta F investigator.; Benevento A investigator.; Cantafio S investigator.; D'Amico FE investigator.; Cesari MC investigator.; Rubbini M investigator.; Salamone G investigator.; Chetta G investigator.; De Marchi F investigator.; Nora MF investigator.; Sousa HS investigator.; Nascimento CA investigator.; Casimiro CAO investigator.; Costa SD investigator.; Rosa MJ investigator.; Carvalho NMD investigator.; Correia JCF investigator.; Gomes AP investigator.; Hill AD investigator.; Walsh TN investigator.; Aremu MA investigator.; Mulsow J investigator.; El‐Masry S investigator.; Gillick J investigator.; Garvin J investigator.; Caldwell M investigator.; Mehigan B investigator.; Winter DC investigator.; Peirce CB investigator.; Cooke F investigator.; Mealy K investigator.; Ruano A investigator.; Ais G investigator.; Fueyo J investigator.; Redondo E investigator.; Sainz B investigator.; Parajó AE investigator.; Landaluce‐Olavarria A investigator.; Bernal‐Sprekelsen JC investigator.; Cordoba E investigator.; Monzón‐Abad JA investigator.; Cerdán‐Santacruz C investigator.; Blanco F investigator.; Veres T investigator.; Abellán A Melero investigator.; Arroyo A investigator.; Ruiz‐Marín M investigator.; Menendez P investigator.; Bazán‐Hinojo MC investigator.; Navas‐Cuéllar JA investigator.; Ramos‐Bernado MI investigator.; Lopez‐Ruiz JA investigator.; Golda T investigator.; Julià D investigator.; Cuadrado MM investigator.; Espin‐Basany E investigator.; Fernández‐Martínez D investigator.; Bravo‐Gutiérrez AF investigator.; Gómez‐Abril SA investigator.; Dujovne P investigator.; Martinez J investigator.; Aguayo JL investigator.; Millan M investigator.; Alvarez‐Gallego M investigator.; Muinelo‐Lorenzo M investigator.; Parra JI Martin investigator.; Muñoz‐Muñoz E investigator.; De Chaves‐Rodríguez PE González investigator.; Cánovas‐Moreno G investigator.; Rodriguez‐Lopez M investigator.; Segura‐Sampedro JJ investigator.; García‐Granero A investigator.; Redondo‐Calvo FJ investigator.; Tallon‐Aguilar L investigator.; Garcea A investigator.; Dyson S investigator.; Thakur D investigator.; Sreedharan L investigator.; Swords C investigator.; Siaw O investigator.; Zelazek M investigator.; Woo R investigator.; Badran A investigator.; Aruparayil N investigator.; Christopoulos P investigator.; Chambers B investigator.; O'Neill N investigator.; Long RH investigator.; Gray RT investigator.; Mccaughey P investigator.; Wong MJ Lynch investigator.; Mccain RS investigator.; Lennox‐Warburton HC investigator.; Moore C investigator.; Manektella KM investigator.; Kamande IW investigator.; Mcilwaine S investigator.; Rupani S investigator.; Simpson DJ investigator.; Wauchope J investigator.; Ng M investigator.; Christian L investigator.; Crone A investigator.; Haddow JB investigator.; Sacks R investigator.; Nazarian S investigator.; Symons NRA investigator.; Lazzaro A investigator.; Patil SD investigator.; Dar FA investigator.; Roomi S investigator.; Silva I investigator.; Hodgson JM investigator.; Ly C investigator.; Misky AT investigator.; Froud H investigator.; Patel H investigator.; Arunachalam S investigator.; Cay P investigator.; Karwal RS investigator.; Arunachalam S investigator.; Danquah‐Boateng D investigator.; Berry BJM investigator.; Esmail HD investigator.; Twum‐Barima CS investigator.; Maripi H investigator.; Bilku D investigator.; McKelvie MA investigator.; Miller K investigator.; Maina A investigator.; Velho R investigator.; Hasan R investigator.; Clingan R investigator.; Jah SMH investigator.; Waite K investigator.; Jones A investigator.; Buckley‐Jones S investigator.; Lecky‐Thompson L investigator.; Connor KL investigator.; Saghir N investigator.; Mansoor S investigator.; Mistry D investigator.; Brown R investigator.; Wong A investigator.; Gurung S investigator.; Wensley F investigator.; Fleming TA investigator.; Griggs RKL investigator.; Kosti A investigator.; Haines S investigator.; Bedoya S investigator.; Beverstock A investigator.; Johnson J investigator.; Elshaer M investigator.; Govind G investigator.; Niaz O investigator.; Colvin DA investigator.; Dyal ARS investigator.; Tokidis E investigator.; Punj S investigator.; Leusink A investigator.; Yeung KTD investigator.; Rudland I investigator.; Kelly M investigator.; Morgan R investigator.; Al‐Musawi S investigator.; Lek C investigator.; Gilbert A investigator.; Gosal A investigator.; Mahoney R investigator.; Parwaiz I investigator.; Morrison TEM investigator.; Mitchard MJ investigator.; Ribeiro B investigator.; Merai H investigator.; Dean EA investigator.; Khan S investigator.; Baginski A investigator.; Mann C investigator.; Foers W investigator.; Jones L investigator.; Woodward B investigator.; Mcwhirter DM investigator.; Thomas AT investigator.; Gilbert TG investigator.; Weatherburn LW investigator.; Pilkington JP investigator.; Cameron FC investigator.; Gilbert TM investigator.; Chean CS investigator.; Clements JM investigator.; Clements JD investigator.; Mccann C investigator.; Davidson S investigator.; Hackney L investigator.; Clements JS investigator.; Martin A investigator.; Hicks G investigator.; Du DT investigator.; Shakoor Z investigator.; Yen SK investigator.; Adnan M investigator.; Ranathunga S investigator.; Sana S investigator.; Tay YH investigator.; Chin MY investigator.; Gillespie M investigator.; Brown AG investigator.; Campbell U investigator.; Assaf N investigator.; Chatzikonstantinou M investigator.; Mahendran B investigator.; Flack T investigator.; Chowdhary M investigator.; Lim JM investigator.; Macinnes EGE investigator.; Whiteman E investigator.; Shepherd JA investigator.; Pedder A investigator.; Thavanesan N investigator.; Siggens KL investigator.; Lai CW investigator.; Morrison‐Jones V investigator.; Hayat Z investigator.; Dubois AS investigator.; Nehikhare I investigator.; Macleod C investigator.; Quinn HC investigator.; Brown A investigator.; Neagle G investigator.; Palani‐Velu LK investigator.; Chok SM investigator.; Carrano FM investigator.; Abbassi OA investigator.; Divekar GA investigator.; Halmer S investigator.; Yow LPS investigator.; Pento V investigator.; Adams RE investigator.; Davies PL investigator.; Wong SY investigator.; Amarasinghe R investigator.; Tague LE investigator.; Jones E investigator.; Radwan RW investigator.; Martin A investigator.; Jones E investigator.; Jamieson NB investigator.; Singh J investigator.; Boza K investigator.; Kelly SD investigator.; Morrison F investigator.; Chan W Hei investigator.; Blencowe NS investigator.; Abdelrahman M investigator.; Wilson EJ investigator.; Awokoya OO investigator.; Griffiths SN investigator.; Kirkham EN investigator.; Cotton AE investigator.; Adimonye A investigator.; Leighton PA investigator.; Lee KA investigator.; Abdelrahman A investigator.; Cartwright H investigator.; Gates Z investigator.; Miguras M investigator.; Zarka ZA investigator.; Khan K investigator.; Louw C investigator.; Grove T investigator.; Badenoch T investigator.; Mckeon J investigator.; Mcdowall NA investigator.; Wood CS investigator.; Leitch RP investigator.; Sgardelis P investigator.; Perera MI investigator.; Nagarajan D investigator.; Malam Y investigator.; Theodoropoulou K investigator.; Venn ML investigator.; Rajagopal S investigator.; Kaptanis S investigator.; Popova D investigator.; Olagbaiye O investigator.; Tayeh S investigator.; Rigby S investigator.; Ashmore DL investigator.; Harris MP investigator.; Whitehorn SE investigator.; Ren KZ investigator.; Liaw G investigator.; Zhou S investigator.; White F investigator.; Golder AM investigator.; Marshall CM investigator.; Mitchell JH investigator.; Anderson DJ investigator.; Kanakala V investigator.; Hollingsworth A investigator.; Paramasevon KR investigator.; Milward J investigator.; Ahmed S investigator.; Delimpalta C investigator.; Fanibi BF investigator.; Ferguson N investigator.; Dickson EA investigator.; Shaw AV investigator.; Kay OH investigator.; Dixon F investigator.; Morrish S investigator.; Dandy R investigator.; Fooks P investigator.; Sharma P investigator.; Islam N investigator.; Tabain V investigator.; Keegan R investigator.; Sarmah P investigator.; Ahel J investigator.; Alhammali T investigator.; Graveston J investigator.; Balai EJ investigator.; Graveston J investigator.; Shah SM investigator.; Rothnie K investigator.; Pankin GP investigator.; Eiben IE investigator.; Jackson NJ investigator.; Dhar M investigator.; Nash D investigator.; Doyle C investigator.; Dharamavaram S investigator.; Seth M investigator.; Chowdhury F investigator.; Rezacova M investigator.; Seneviratne N investigator.; Turner EJ investigator.; Currow C investigator.; Issa E investigator.; Isherwood JD investigator.; Hobson BM investigator.; West H investigator.; Lui DH investigator.; Nana GR investigator.; Rodger V investigator.; Ting N investigator.; Brewer HK investigator.; Photiou D investigator.; Farrow EZ investigator.; Taze D investigator.; Lodhia S investigator.; Earnshaw L investigator.; Kumar K investigator.; Neale A investigator.; Bastianpillai J investigator.; Cipparrone M investigator.; Barrie A investigator.; Taylor NS investigator.; Nash Z investigator.; Anandan L investigator.; Tailor K investigator.; Vinnicombe Z investigator.; Krivan S investigator.; Kuo R investigator.; Giorga A investigator.; Habib H investigator.; Malik K investigator.; Bogdan M investigator.; Mahon‐Daly FP investigator.; Athersmith MJ investigator.; Strange JA investigator.; Griffiths NP investigator.; Wheeler C investigator.; Summerfield L investigator.; Khaw RA investigator.; Ashour O investigator.; Iosif E investigator.; Fadel M investigator.; Gopalakrishnan K investigator.; Orme N investigator.; Williams S investigator.; Rashid M investigator.; Sultana A investigator.; Patel N investigator.; Knight SR investigator.; Pearson R investigator.; Yasin T investigator.; Bevan V investigator.; Mowbray NG investigator.; Al‐Sarireh B investigator.; Olivier JB investigator.; Brown M investigator.; Mohd N investigator.; Howie EE investigator.; Poudevigne M investigator.; Paget C investigator.; Rallage H investigator.; Chui K investigator.; Fawzi F investigator.; Layman S investigator.; Okorocha E investigator.; Jama GM investigator.; Orawiec P investigator.; Kouli O investigator.; Hassane A investigator.; Clement KD investigator.; Kilkenny J investigator.; Devine AA investigator.; Laurenson M investigator.; Slezak I investigator.; Barker T investigator.; Lau EYL investigator.; Limbada M investigator.; O'Brien J investigator.; Weaver J investigator.; Barker T investigator.; Panda N investigator.; Hajibandeh S investigator.; Shah J investigator.; Mansour MM investigator.; Malik SN investigator.; Davis S investigator.; Trew F investigator.; Bandyopadhyay SK investigator.; Dart K investigator.; Connor MJ investigator.; Guru‐Naidu S investigator.; Callan R investigator.; Nair MK investigator.; Alani M investigator.; Sezen E investigator.; Salim S investigator.; Fahmy SE investigator.; Shurlock J investigator.; Siddique K investigator.; Forouzanfar A investigator.; Brews R investigator.; Ngu WS investigator.; Acharya A investigator.; Jain A investigator.; Adegbola SO investigator.; Sahnan K investigator.; Tozer PJ investigator.; Warusavitarne J investigator.; Emslie KM investigator.; Collier‐Wakefield O investigator.; Sivaloganathan P investigator.; Dobson C investigator.; Elseedawy M investigator.; Vaughan EM investigator.; Stupalkowska W investigator.; McNally L investigator.; Williams M investigator.; Motiwala FH investigator.; Choi S investigator.; Asmadi A Ahmad investigator.; Burnside D investigator.; Everden A investigator.; Suriyakumar S investigator.; Sandu L investigator.; Kent DA investigator.; Bowen J investigator.; Simmonds LFC investigator.; Long P investigator.; Khair A investigator.; Malik A investigator.; Shah K investigator.; Phelan L investigator.; Pierre R investigator.; Dhari AA investigator.; Hussein A investigator.; Hoff M investigator.; Karim MJ investigator.; Nickson S investigator.; Setshwaelo T investigator.; Chalk A investigator.; Parkola MJ investigator.; Harlinska A investigator.; Chan TCW investigator.; Dudek JG investigator.; Rolph R investigator.; Allen M investigator.; Pollard H investigator.; Ormiston R investigator.; Gormely R investigator.; Finlayson H investigator.; Ljungqvist G investigator.; Peponis C investigator.; Glasbey JC investigator.; Tyler R investigator.; Rahman MMA investigator.; Dhesi S investigator.; Mohamed MS Noor investigator.; Arshad F investigator.; Wilkin RJW investigator.; Faris AR investigator.; Sooriyamoorthy T investigator.; Kung VWS investigator.; Springate EL investigator.; Barnieh W investigator.; Patel AS investigator.; Siddiqui ZA investigator.; Chishti IA investigator.; Ayube‐Brown J investigator.; Rabie MR investigator.; Blake L investigator.; Yardimci E investigator.; Nagendram S investigator.; Park JH investigator.; Neophytou GI investigator.; Henderson L investigator.; Farhan‐Alanie MMH investigator.; Kong CY investigator.; Ghazala R investigator.; Lal N investigator.; Evans J investigator.; Hussain N investigator.; Kabir M investigator.; Worku D investigator.; Hraishawi I investigator.; D'Auria M investigator.; Cox M investigator.; Bailey JA investigator.; Muhibullah N investigator.; Yanni F investigator.; Ang A investigator.; Orizu M investigator.; Stevenson R investigator.; Nair A investigator.; Murphy C investigator.; Mcgucken O investigator.; Gammeri E investigator.; Pandya R investigator.; Bowerman H investigator.; Lafaurie G investigator.; Van Boxel GI investigator.; Shanmugarajah K investigator.; Maragouthakis D investigator.; Hanif Z investigator.; Evans JD investigator.; Yoganathan S investigator.; Richardson TD investigator.; Choy CH investigator.; Cook V investigator.; Clark GL investigator.; Rigney B investigator.; O'Neill E investigator.; Guliani J investigator.; Herrod PJJ investigator.; Chan D investigator.; Harper F investigator.; Sian T investigator.; Boereboom C investigator.; Blackwell JEM investigator.; Hardy E investigator.; Boyd‐Carson H investigator.; Couch DG investigator.; Barter CA investigator.; Thoukididou SN investigator.; Hatt JR investigator.; Jones CS investigator.; Dean S investigator.; Rajaretnam N investigator.; Lawday S investigator.; Masood M investigator.; Thakral N investigator.; Griffith D investigator.; Doherty C investigator.; Longshaw A investigator.; Peprah D investigator.; Mathew G investigator.; Hann AJ investigator.; Hook A investigator.; Robinson D investigator.; Vance‐Daniel J investigator.; Ibrahim YMS investigator.; Wardle BG investigator.; Walters KJ investigator.; Whewell HE investigator.; Sherif MA investigator.; Mckenna M investigator.; Pearce JCH investigator.; O'Sullivan D investigator.; Woodrow C investigator.; Gill S investigator.; Johnstone A investigator.; Gentry R investigator.; Irwin R investigator.; Forgie A investigator.; Welsh S investigator.; Hickey LM investigator.; Ivey P investigator.; Bullivant JK investigator.; English WJ investigator.; Osterberg A investigator.; Morowala A investigator.; Al‐Faham Z investigator.; Islam S investigator.; Tan E investigator.; Garg AG investigator.; Sadek S investigator.; Sihra N investigator.; Shrestha D investigator.; Chong B investigator.; Nadeem A investigator.; Fasuyi JA investigator.; Patel MM investigator.; Daureeawoo R investigator.; Okekunle B investigator.; Cheruvu M investigator.; Mazumdar E investigator.; Mahmood F investigator.; Hussain A investigator.; Patel C investigator.; Mcquaid M investigator.; Banks A investigator.; Robinson A investigator.; Khan MS investigator.; Riaz W investigator.; Verroiotou M investigator.; Cohen JA investigator.; Kouroumpas E investigator.; Rehman S investigator.; Donaldson G investigator.; Ghaffari I investigator.; Moradzadeh J investigator.; Peleki A investigator.; Kamal M investigator.; Gulamhussein M investigator.; Pearce L investigator.; Gaines E investigator.; Ghatorae S investigator.; Clark S investigator.; Sharp OL investigator.; Savill A investigator.; Hutchinson B investigator.; Chapman J investigator.; Wu F investigator.; Creasy W investigator.; Raymond M investigator.; Grosvenor S investigator.; Odeh A investigator.; Malik Y investigator.; Bansal H investigator.; Grant C investigator.; Raofi A investigator.; Ahmed B investigator.; Mai D investigator.; Thompson DB investigator.; Souter JEH investigator.; Hamelmann RN investigator.; Ikram S investigator.; El‐Tayar O investigator.; De‐Manzoni‐Garberini A investigator.; Hollyman M investigator.; Durbacz M investigator.; Gilliland N investigator.; Salem A investigator.; Chudek D investigator.; Rupasinghe SN investigator.; Ladwa N investigator.; Storey R investigator.; Fontaine C investigator.; Toomey D investigator.; Miller B investigator.; Robinson A investigator.; Oakey M investigator.; Smoker H investigator.; Amtul N investigator.; Chapman SJ investigator.; O'Hagan SC investigator.; Tahir W investigator.; Wilcox GJA investigator.; Ahmad A investigator.; Akram F investigator.; Baddams TS investigator.; Boshier PR investigator.; Fehervari M investigator.; Easdon S investigator.; Mersh RJ investigator.; Ilozue T investigator.; Adam ME investigator.; Newton RC investigator.; Jokhan S investigator.; Foster A investigator.; Nambiar K investigator.; Bohra P investigator.; Janardanan S investigator.; Shanmuganathan V investigator.; Maqboul F investigator.; Ettles C investigator.; Wardle SD investigator.; Martinou E investigator.; Stephens GF investigator.; Khasria A investigator.; Bagga R investigator.; Motter D investigator.; Mundkur N investigator.; Pan Y investigator.; Abbas SH investigator.; Akbari K investigator.; Farrell SM investigator.; Rahim A investigator.; Gummaraju A investigator.; Iqbal MR investigator.; Mahmoud A investigator.; Akinsola O investigator.; Smallcombe N investigator.; Tarazi M investigator.; Hanley C investigator.; Brown CE investigator.; Campbell UM investigator.; Mckinley NC investigator.; Renshaw S investigator.; Franklin D investigator.; Davidson JR investigator.; Hureibi KA investigator.; Raza SS investigator.; Krishnamoorthy A investigator.; Rajjoub Y investigator.; Ali M investigator.; Seddon TC investigator.; Payne RE investigator.; Das A investigator.; Martin LM investigator.; Naismith KN investigator.; Venkata UP Pullabatla investigator.; Manda VM investigator.; Donohoe N O investigator.; Burns KM investigator.; Huang J investigator.; Samuel M investigator.; Docherty JA investigator.; Cheah WL investigator.; Ooi R investigator.; Nyeko‐Lacek M investigator.; Marsh L investigator.; Prideaux A investigator.; Li CH investigator.; Poacher A investigator.; Lee M investigator.; Muzaffar M investigator.; Egan RJ investigator.; Kara A investigator.; Walsh E investigator.; Kara A investigator.; Sunter H investigator.; Roth NPG investigator.; Roy C investigator.; Mcmorran D investigator.; Turnbull A investigator.; Trail M investigator.; Layton GR investigator.; Archer JE investigator.; Yang P investigator.; Engall NFT investigator.; Henderson L investigator.; Douka E investigator.; Amin V investigator.; Borghol K investigator.; Marriott P investigator.; Townsend DC investigator.; Blackford OD investigator.; Bond S investigator.; Baker B investigator.; Mohamed WO investigator.; Williams R investigator.; Garnham J investigator.; Patel BY investigator.; Robb HD investigator.; Allington J investigator.; Cloney L investigator.; Tamborska A investigator.; Kalia K investigator.; Fung EJM investigator.; Johnston Z investigator.; Lynch L investigator.; Christides A investigator.; Tan HL investigator.; Cynthia G investigator.; Tsang B investigator.; Rossi C investigator.; Kaubrys M investigator.; Al‐Khafaji N investigator.; Jenkins M investigator.; Choong JH investigator.; Chok SM investigator.; Peiris GB investigator.; Mohamed TM investigator.; Gunning S investigator.; Nimako E investigator.; Pandya D investigator.; Hever P investigator.; Amayo A investigator.; Bull C investigator.; Hudson‐Peacock NJ investigator.; Clements C investigator.; Al‐Sheikh M investigator.; Savioli F investigator.; Long M investigator.; Horsfield E investigator.; Robertson C investigator.; Ogboru S investigator.; Mcilwrath AC investigator.; Bhanderi S investigator.; Bailey S investigator.; Bell J investigator.; Hebbar KRM investigator.; Limb C investigator.; Obeid N investigator.; Rich JE investigator.; Balasubramaniam A investigator.; Mothe BS investigator.; Mashar R investigator.; Taylor M investigator.; Bruce JR Schuster investigator.; Weegenaar CR investigator.; Dennison G investigator.; Curtis NJ investigator.; Saad M investigator.; Ezerska E investigator.; Ellis B investigator.; Brown M investigator.; Wiggill S investigator.; Tee A investigator.; Ng S investigator.; Carder CFW investigator.; Abdelwahed A investigator.; Bowman CR investigator.; Chandler SB investigator.; Tinsley BJ investigator.; Savino G investigator.; Finotti E investigator.; Serventi F investigator.; Occhioni G investigator.; Cossu F investigator.; Vulcano I investigator.; 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• Is Part Of: British journal of surgery. Volume 107:Issue 1(2020)
• Page Start: 73
• Page End: 86
• Publication Date: 2019-12-03
• Subjects: Surgery -- Periodicals; 617.005
• DOI: 10.1002/bjs.11440
• Languages: English
• ISSNs: 0007-1323

Abstract

Abstract : Background: Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods: A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results: Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion: Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified. Abstract : Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making were identified by identifying UK adults at low risk of appendicitis. An online calculator is available (http://appy‐risk.org ). WCC, white cell count; CRP, C‐reactive protein; AIRS, Appendicitis Inflammatory Response Score; AAS, Adult Appendicitis Score. Important differences between men and women Abstract : Antecedentes: La apendicitis es la urgencia quirúrgica de cirugía general más frecuente en todo el mundo, pero su diagnóstico sigue siendo un desafío. El objetivo de este estudio fue determinar si los modelos de predicción de riesgo existentes pueden identificar de manera fiable a los pacientes del Reino Unido que se presentan en el hospital con dolor agudo en la fosa ilíaca derecha (right iliac fossa, RIF) con bajo riesgo de apendicitis. Métodos: Se realizó una búsqueda sistemática para identificar todos los modelos existentes de predicción de riesgo de apendicitis. Los modelos se validaron utilizando los datos del Reino Unido de un estudio International prospectivo de cohortes que incluía pacientes consecutivos de 16 a 45 años que se presentaron en el hospital con dolor agudo en RIF entre marzo y junio de 2017. El criterio de valoración principal fue la mejor especificidad que era posible alcanzar con el modelo (proporción de pacientes que no tenían apendicitis correctamente clasificados como de bajo riesgo) manteniendo una tasa de fracaso < 5% (proporción de pacientes identificados como de bajo riesgo que realmente tuvieron apendicitis). Resultados: Se identificaron 5.345 pacientes en 154 hospitales del Reino Unido, de los cuales dos tercios (67, 6%, 3.613/5.345) eran mujeres. Las mujeres tenían más del doble de probabilidades de someterse a una apendicectomía con un apéndice histológicamente normal (28, 2%; 272/964) en comparación con los varones (12, 1%; 120/993, riesgo relativo 2, 33 (i.c. del 95% 1, 92‐2, 84), P < 0, 001)). Entre los 15 modelos de predicción de riesgo validados, el sistema de puntuación de apendicitis en adultos (Adult Appendicitis Score) fue el que obtuvo la mejor predicción (punto de corte ≤ 8, especificidad 63%, tasa de fracaso 3, 7%). El sistema de puntuación de la respuesta inflamatoria de apendicitis (Appendicitis Inflammatory Response Score) fue el que obtuvo la mejor predicción en los varones (punto de corte ≤ 2, especificidad 25%, tasa de fracaso 2, 4%). Conclusión: Las mujeres del Reino Unido tuvieron un riesgo desproporcionado de ingreso sin intervención quirúrgica, así como porcentajes elevados de apendicectomías blancas. Se encontraron modelos de predicción de riesgos para apoyar la toma de decisiones compartida mediante la identificación de adultos del Reino Unido con bajo riesgo de apendicitis.