Sacral anatomical interspace landmark for lumbar puncture in pregnancy: A randomized trial. (11th February 2020)

• Record Type: Journal Article
• Authors: Pancaro, Carlo; Rajala, Baskar; Vahabzadeh, Christie; Cassidy, Ruth; Klumpner, Thomas T.; Kountanis, Joanna A.; McCabe, Madeline; Rector, Dana; Aman, Casey; Sankar, Keerthana; Schoenfeld, Robert; Engoren, Milo
• Is Part Of: Neurology. Volume 94:Number 6(2020)
• Publication Date: 2020-02-11
• Subjects: Neurology -- Periodicals; Neurology -- Periodicals; Neurologie -- Périodiques; 616.8
• DOI: 10.1212/WNL.0000000000008749
• Languages: English
• ISSNs: 0028-3878

Abstract

Abstract : Objective: To determine whether the sacral anatomical interspace landmark (SAIL) technique is more accurate than the classic intercristal line (ICL) technique in pregnant patients and to assess the percentage of clinical determinations above the third lumbar vertebra. Methods: In this prospective, randomized, open-label trial, there were 110 singleton pregnant patients with gestational age greater than 37 weeks included. Selection procedure was a convenience sample of pregnant patients who presented for office visits or vaginal or cesarean delivery between March 15 and July 31, 2018, at a single-center obstetric tertiary care university hospital. Both techniques were evaluated by 2 physicians independently assessing each method. Before data collection, we hypothesized that the SAIL technique would be more accurate than the ICL technique in determining the L4-L5 interspace, and that the SAIL technique would produce more estimations below the third lumbar vertebra than the ICL technique. Therefore, the primary outcome was accuracy in identifying the L4-L5 lumbar interspace with SAIL vs ICL. The secondary outcome was difference in clinical assessments above the third lumbar vertebra. Both outcomes were measured via ultrasonography. Results: Patients were 31 ± 5 years of age (mean ± SD) and had body mass index of 31.8 ± 5.7 kg/m 2 and gestational age of 38.8 ± 1.1 weeks. A total of 110 patients were analyzed. SAIL correctly identified the L4-L5 interspace 49% of the time vs 8% using ICL ( p < 0.0001). Estimations above L3 were 1% for SAIL vs 31% for ICL ( p < 0.0001). Conclusions: Our study shows improved accuracy in identifying intervertebral space using the SAIL technique; this may prevent direct mechanical trauma to the conus medullaris when lumbar punctures are performed in pregnancy. Clinicaltrials.gov identifier: NCT03433612.