Thyroid-Associated Ophthalmopathy after Radioactive Iodine Therapy for Metastatic Follicular Thyroid Carcinoma. (11th June 2021)

• Record Type: Journal Article
• Authors: Murayama, Daisuke; Toda, Soji; Okubo, Yoichiro; Hayashi, Hiroyuki; Matsui, Ai; Yasukawa, Mio; Iwasaki, Hiroyuki
• Other Names: Deandreis Désirée Academic Editor.
• Is Part Of: Case reports in endocrinology. Volume 2021(2021)
• Publication Date: 2021-06-11
• Subjects: Endocrinology -- Periodicals; Endocrinology -- Case studies -- Periodicals; Endocrine glands -- Diseases -- Periodicals; Endocrinology; Endocrine System Diseases; Endocrine glands -- Diseases; Endocrinology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.4
• DOI: 10.1155/2021/3024639
• Languages: English
• ISSNs: 2090-6501

Abstract

Abstract : Thyroid-associated ophthalmopathy (TAO) is an inflammation of the extraocular muscles and periorbital connective tissue caused by autoantibodies against common antigens to both the thyroid and orbit. The release of antigens and induction of hypothyroidism caused by radioactive iodine (RAI) therapy may exacerbate TAO. Here, we present the case of a 67-year-old-woman treated with RAI therapy for metastatic follicular thyroid carcinoma who presented with TAO during the course of sorafenib administration. Tg and TgAb levels were gradually decreased with sorafenib and lenvatinib treatment, and TAO was improved without any ophthalmologic treatment.