The Importance of the Temporal Bone 3T MR Imaging in the Diagnosis of Menière's Disease. Issue 2 (February 2020)

• Record Type: Journal Article
• Authors: Paškonienė, Aistė; Baltagalvienė, Renata; Lengvenis, Givi; Beleškienė, Vilma; Ivaška, Justinas; Markevičiūtė, Vėtra; Mickevičienė, Vaiva; Lesinskas, Eugenijus
• Is Part Of: Otology & neurotology. Volume 41:Issue 2(2020)
• Publication Date: 2020-02
• Subjects: Endolymphatic hydrops -- Magnetic resonance imaging -- Menière's disease; Otology -- Periodicals; Ear -- Diseases -- Periodicals; Skull base -- Surgery -- Periodicals; 617.8005
• DOI: 10.1097/MAO.0000000000002471
• Languages: English
• ISSNs: 1531-7129

Abstract

Abstract : Background: The aim of this study was to evaluate endolymphatic hydrops using the 3T temporal bone magnetic resonance imaging (MRI), performed according to the chosen protocol, and determine whether it could be applied as an objective diagnostic tool for Menière's disease. Methods: 105 participants diagnosed with probable (n = 50) and definite (n = 55) Menière's disease were included in this prospective study at Vilnius University Hospital, Santaros Clinics. Audiometry, vestibular function tests, videonystagmography, and computer posturography were performed before MRI. The 3T MRI with gadolinium contrast was performed to evaluate the endolymphatic hydrops. Imaging protocol consisted of 3D-FLAIR and 3D T2DRIVE sequences. Vestibular endolymphatic sac was interpreted as enlarged if occupied more than 50% of the vestibular area. Results: 78.1% of subjects had abnormal MRI findings other than hydrops, and it was more than 90% (50/55) of patients in the definite MD group ( p < 0.001). Changes in caloric test were observed in 63.8% of subjects in general, and in 76.4% of patients with a definite Menière's disease. The side of the endolymphatic hydrops observed on MR imaging corresponded to the clinical diagnosis of the Menière's disease based on the results of audiometry ( p < 0.001) and unilateral weakness ( p < 0.001). Endolymphatic hydrops on MRI and directional preponderance in caloric test were two independent predictors of the definite Menière's disease. Conclusions: Temporal bone 3T MRI with gadolinium contrast is clinically superior to confirm the diagnosis of Menière's disease. Grade II endolymphatic hydrops on MRI, directional preponderance, and unilateral weakness on caloric test were independent predictors for the definite Menière's disease.