Iron‐Catalyzed Synthesis of Dihydronaphthalenones from Aromatic Oxime Esters. Issue 13 (30th April 2019)

• Record Type: Journal Article
• Authors: Zhang, Youcan; Yin, Zhiping; Wu, Xiao‐Feng
• Is Part Of: Advanced synthesis & catalysis. Volume 361:Issue 13(2019)
• Page Start: 3223
• Page End: 3227
• Publication Date: 2019-04-30
• Subjects: Iron -- Radical -- Dihydronaphthalenone -- Oxime Ester -- Cyclization; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201900283
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Herein, a convenient procedure on iron‐catalyzed radical‐mediated synthesis of dihydronaphthalenones from oxime esters has been developed. By using iron salt as a green and inexpensive catalyst, various α‐aryl oxime esters were transformed into the corresponding dihydronaphthalenones in moderate to good yields with high chemo‐selectivities. The reaction proceeds via 1, 5‐hydrogen atom transfer and then intramolecular radical cyclization sequence. Abstract :