A second primary squamous cell carcinoma arising in the skin of a pectoralis major myocutaneous flap 20 years after tongue reconstruction. Issue 4 (July 2021)

• Record Type: Journal Article
• Authors: Nakaue, Kazuhiko; Yamakawa, Nobuhiro; Imada, Mitsuhiko; Ueda, Nobuhiro; Yagyuu, Takahiro; Nakayama, Yohei; Kirita, Tadaaki
• Is Part Of: Journal of oral and maxillofacial surgery, medicine, and pathology. Volume 33:Issue 4(2021)
• Page Start: 448
• Page End: 453
• Publication Date: 2021-07
• Subjects: CT computed tomography -- DP deltopectoral -- PET positron emission tomography -- PMMC pectoralis major myocutaneous -- SCC squamous cell carcinoma -- SUV standardized uptake value; Squamous cell carcinoma -- Secondary primary carcinoma -- Pectoralis major myocutaneous flap -- Oral cavity -- Metaplastic transformation; Mouth -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Oral medicine -- Periodicals; Mouth -- Diseases -- Pathogenesis -- Periodicals; Surgery, Oral -- Periodicals; Oral Medicine -- Periodicals; Pathology, Oral -- Periodicals; Face -- Surgery; Maxilla -- Surgery; Mouth -- Diseases -- Pathogenesis; Mouth -- Surgery; Oral medicine; Electronic journals -- Sciences; Electronic journals -- Medicine; Periodicals; 617.522059
• DOI: 10.1016/j.ajoms.2021.02.006
• Languages: English
• ISSNs: 2212-5566

Abstract

Abstract: A 54-year-old man presented with a second primary tongue squamous cell carcinoma, which developed in the pectoralis major myocutaneous flap used for the reconstruction of the right side of the tongue 20 years previously. The patient had originally undergone concurrent chemoradiotherapy and subtotal glossectomy. We believe that the carcinoma was likely caused by metaplastic transformation of the flap skin due to its chronic exposure to stimuli not normally experienced by the skin. The findings in this case suggest that patient education and long-term follow-up are required following flap reconstruction in cases of advanced oral cancer.