Dedicated 70 MHz RF systems for hyperthermia of challenging tumor locations. Issue 9 (13th November 2020)

• Record Type: Journal Article
• Authors: Crezee, Johannes; Zweije, Remko; Sijbrands, Jan; Kok, H. Petra
• Editors: Macháč, J.; Švanda, M.; Vbra, J.
• Is Part Of: International journal of microwave and wireless technologies. Volume 12:Issue 9(2020)
• Page Start: 839
• Page End: 847
• Publication Date: 2020-11-13
• Subjects: hyperthermia, -- RF heating, -- MW heating, -- semi-deep seated tumours; Wireless communication systems -- Periodicals; Microwave circuits -- Periodicals; Radio frequency -- Periodicals; 621.381305
• DOI: 10.1017/S1759078720000318
• Languages: English
• ISSNs: 1759-0787

Abstract

Abstract: Hyperthermia (i.e. heating of tumor tissue to 40–43°C) is used in clinical oncology to enhance the therapeutic effect of chemotherapy and radiotherapy. Many tumor sites are heated either by a single RF or MW antenna positioned on the tumor location, or by a phased array positioned around the patient. Superficial tumors are generally heated with MW antennas (434–2450 MHz) and deep-seated tumors with RF antennas (70–150 MHz). These devices cover the major, more common tumor sites, but more rare locations require more dedicated applicators. We discuss dedicated RF systems aiming for heating semi-deep-seated tumors in the leg, breast, and upper thorax. Clinical results show that adequate heating is possible with these systems, with achieved temperatures in the therapeutic range.