Use of Vaginal Reconstructive Surgery in Cervical Cancer Patients to Prevent Vaginal Stump Contracture. Issue 7 (9th August 2021)

• Record Type: Journal Article
• Authors: Wang, Zhi; Zeng, Ang; Long, Fei; Wu, Ming; Tan, Xian-Jia; Liu, Zi-Wen; Wang, Xiao-Jun
• Is Part Of: Journal of investigative surgery. Volume 34:Issue 7(2021)
• Page Start: 747
• Page End: 753
• Publication Date: 2021-08-09
• Subjects: Cervical cancer -- radiotherapy -- vaginal extension with ileal graft -- vaginal stump contracture; Surgery -- Research -- Periodicals; Research; Surgery; Surgical Procedures, Operative; 617.075
• DOI: 10.1080/08941939.2019.1683658
• Languages: English
• ISSNs: 0894-1939

Abstract

Abstract: Purpose: The life quality of cervical cancer patients is severely compromised due to the vaginal stump contracture after surgery combined with radiotherapy. Therefore, our study focuses on ameliorating or preventing postoperative vaginal contracture. The objectives of this study were (1) to evaluate the method of ileal graft with vascular pedicle to extend the length of vagina and (2) to investigate the effect of the operation to prevent vaginal stump contracture after cervical cancer surgery combined with radiotherapy. Methods: Twenty-five patients with vaginal stump contracture after cervical cancer radical resection with sequential radiotherapy were recruited for the study between 2011 and 2014. The therapy includes releasing the adhesion between vaginal stump and rectum as well as bladder, resecting the vaginal stump but reserving the exterior orifice of vagina, and extending the vaginal length using vascularized ileal graft. Results: No postoperative complications such as infection and bleeding were observed in all 25 patients. The patients were satisfied with the length and width of vagina after extension; the discharge of reconstructed vagina was acceptable. All patients had sexual intercourse on the follow-up examination, and five patients complained of vaginal bleeding during or after sexual intercourse, although no abnormality was found on colposcopy. Conclusions: The patients demonstrated a high level of safety, efficacy, and satisfaction with the ileal–vaginal extension for treating vaginal stump contracture after cervical cancer surgery combined with radiotherapy, suggesting that this method is valid for broad clinical application to improve the life quality of cervical cancer patients after surgery.