Microneedle Patch Delivery: Microneedle Patch Delivery of Capsaicin‐Containing α‐Lactalbumin Nanomicelles to Adipocytes Achieves Potent Anti‐Obesity Effects (Adv. Funct. Mater. 20/2021). (17th May 2021)

• Record Type: Journal Article
• Authors: Bao, Cheng; Li, Zekun; Liang, Shuang; Hu, Yulin; Wang, Xiaoyu; Fang, Bing; Wang, Pengjie; Chen, Shanan; Li, Yuan
• Is Part Of: Advanced functional materials. Volume 31:Number 20(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-05-17
• Subjects: α‐lactalbumin -- adipose tissue -- anti‐obesity -- capsaicin -- microneedle patch -- nanomicelles; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.202170144
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number 2011130, Yuan Li and co‐workers present a minimally invasive anti‐obesity treatment system that supports local targeting of adipose tissues. The microneedles successfully deliver pepper sourced compound‐capsaicin (Cap) loaded a‐lactalbumin micelles into subcutaneous adipocytes, promoting the "burning" anti‐lipogenesis effect of fat cells by Cap. This delivery system selectively targets adipose and could represent a non‐invasive approach for treating obesity.