A sustainable approach for efficient one‐pot synthesis of 1‐aryl 1, 2, 3‐triazoles using copper iodide supported on 3‐thionicotinyl‐urea‐modified magnetic nanoparticles in DES. (6th April 2021)

• Record Type: Journal Article
• Authors: Mirshafiee, Sogand; Salamatmanesh, Arefe; Heydari, Akbar
• Is Part Of: Applied organometallic chemistry. Volume 35:Number 7(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-04-06
• Subjects: 1‐aryl 1, 2, 3‐triazoles -- 3‐thionicotinyl‐urea‐modified magnetic nanoparticles -- copper(I) catalyst -- deep eutectic solvent; Organometallic chemistry -- Periodicals; Organometallic compounds -- Periodicals; 547.05
• DOI: 10.1002/aoc.6255
• Languages: English
• ISSNs: 0268-2605

Abstract

Abstract : An efficient and retrievable copper(I) catalyst was synthesized by immobilizing of copper iodide on 3‐thionicotinyl‐urea‐modified magnetic nanoparticles and characterized using a variety of analysis techniques. The catalytic activity of these nanoparticles was investigated in the one‐pot three‐component reaction of aryl halides, sodium azide, and terminal alkynes using choline chloride/PEG deep eutectic mixture as a green and recoverable solvent. The PEGylated deep eutectic solvent (DES), due to its favorable polarity and solubility, can make an effective association of polar and non‐polar reactants during the reaction, thereby accelerating the catalysis process. An array of 1‐aryl 1, 2, 3‐triazoles were obtained in good to excellent yields. The catalyst system can be readily recovered and reused at least five times with no appreciable loss of its activity. Abstract : A heterogeneous copper(I) catalyst was developed by immobilizing copper iodide on 3‐thionicotinyl‐urea‐modified magnetic nanoparticles and applied for the efficient synthesis of 1‐aryl 1, 2, 3‐triazoles via the one‐pot three‐component reaction of aryl halides, sodium azide, and terminal alkynes in PEGylated deep eutectic mixture as a green and sustainable solvent. Both the catalyst and solvent can be recovered and reused several times.