Binuclear chiral Ni(II) complex of tridentate OON chiral Schiff base ligand, 1-((E)-(((1S, 2R)-2-hydroxy-2, 3-dihydro-1H-inden-1-yl)imino)methyl)naphthalen-2-ol. Issue 1 (2nd January 2020)

• Record Type: Journal Article
• Authors: Maiti, Subir Kr; Bora, Aditi; Barman, Pranjit; Chandra, Asit K.; Baidya, Bidisha
• Is Part Of: Journal of coordination chemistry. Volume 73:Issue 1(2020)
• Page Start: 67
• Page End: 86
• Publication Date: 2020-01-02
• Subjects: Chiral Schiff base -- computational study -- DNA binding; Coordination compounds -- Periodicals; 541.2242
• DOI: 10.1080/00958972.2019.1711069
• Languages: English
• ISSNs: 0095-8972

Abstract

Abstract: Binuclear Ni(II) chelating complex with chiral Schiff base 1-((E)-(((1S, 2R)-2-hydroxy-2, 3-dihydro-1H-inden-1-yl)imino)methyl)naphthalene-2-ol [Ni2 L2 ] has been synthesized. The structure of [Ni2 L2 ] was elucidated with single-crystal X-ray diffraction, spectroscopic (UV–vis, FTIR, mass) analysis and substantiated with computational (DFT) method. The crystal system of binuclear complex is monoclinic with space group P21/c . The asymmetric unit having two tridentate OON-donor sets are in slightly distorted square-planar geometry around each Ni(II) center. The distortion is due to strong coordination between two Ni(II) ions. The stabilization of complex [Ni2 L2 ] occurs due to noncovalent interactions and hydrogen bonding (C–H…C and C–H…O), H…H, O…H, C…H, and C–H…π stacking interactions, and van der Waals interactions. DFT optimization, with little acceptable discrepancies, correlate with the X-ray diffraction data as well as TD DFT optimization for electronic transitions of the complex showing acceptable alignment with spectroscopic data. The complex displays appreciable inclination towards DNA-binding with calf-thymus DNA (CT DNA) and the DNA-binding studies were carried out by UV–visible spectroscopy, fluorescence spectroscopy, cyclic voltammetry, viscosity measurements, and CD spectroscopy. The DNA-binding study reveals that the order of binding constant value is in 10 5 M − 1, supporting the effective efficiency of binding and the modes of binding are intercalation and groove. Graphical Abstract: UF0001