A New Voltammetric Approach for Electrochemical Determination of Lamotrigine in Pharmaceutical Samples. Issue 6 (22nd March 2021)

• Record Type: Journal Article
• Authors: Ciucu, Anton A.; Buleandră, Mihaela; Ciurea, Tatiana; Stoica, Vlad N.; Ştefanescu, Cristian D.; Ciobanu, Adela
• Is Part Of: Electroanalysis. Volume 33:Issue 6(2021)
• Page Start: 1389
• Page End: 1392
• Publication Date: 2021-03-22
• Subjects: disposable electrode -- voltammetry -- lamotrigine -- pharmaceutical formulation; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.202100037
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: A new linear sweep voltammetric method for quantitative lamotrigine (LMT) determination based on an electrochemically pre‐treated pencil graphite electrode (PGE*) is presented. Response characteristics of the PGE* toward the mentioned compound were investigated by cyclic voltammetry and linear sweep voltammetry. The quantitative determination of LMT revealed a wide linear range of 2.5 ⋅ 10 −5 –1.0 ⋅ 10 −3 M with a detection limit of 1.94 ⋅ 10 −5 M. The method was used successfully for LMT determination in a pharmaceutical formulation. Abstract :