Inkjet-printed paper-based electrochemical sensor with gold nano-ink for detection of glucose in blood serum. (23rd April 2021)

• Record Type: Journal Article
• Authors: Kant, Tushar; Shrivas, Kamlesh; Tapadia, Kavita; Devi, Rama; Ganesan, Vellaichamy; Deb, Manas Kanti
• Is Part Of: New journal of chemistry. Volume 45:Number 18(2021)
• Page Start: 8297
• Page End: 8305
• Publication Date: 2021-04-23
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d1nj00771h
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : An inkjet-printed paper electrode with gold nanoparticle-ink as a non-enzymatic electrochemical sensor for detection of glucose in blood serum is reported. Abstract : Herein, an inkjet-printed paper electrode (PPE) with gold nanoparticle (AuNP)-ink as a non-enzymatic electrochemical sensor for detection of glucose in blood serum is reported. In this work, a green method is used for the synthesis of the aqueous AuNP-ink and the electrode is fabricated on a paper substrate using an office desktop inkjet-printer. The developed AuNP-ink is stable and has a surface tension and viscosity of 70.2 mN m −1 and 2.1 mPa s (2% aqueous AuNP ink). The PPE with AuNPs is sintered at 100 °C for 30 min to obtain a conductive film for electrochemical sensing. The prepared AuNP-PPE is employed as a working electrode in cyclic voltammetry (CV) for the sensitive measurement of glucose in blood serum. The fabricated AuNP-PPE demonstrated excellent electrochemical activity and rapid electron transfer kinetics towards the oxidation of glucose. A wide linear range, 0.05–35 mM, with a limit of detection of 10 μM is observed for the determination of glucose. The advantages of using the AuNP-PPE in electrochemical measurements are that it is flexible, user-friendly, biodegradable, economic and enzyme-free with respect to the commercially available electrochemical sensors.