Are hair follicle stem cells promising candidates for wound healing?. (1st February 2019)

• Record Type: Journal Article
• Authors: Li, Bingmin; Hu, Wenzhi; Ma, Kui; Zhang, Cuiping; Fu, Xiaobing
• Is Part Of: Expert opinion on biological therapy. Volume 19:Number 2(2019)
• Page Start: 119
• Page End: 128
• Publication Date: 2019-02-01
• Subjects: Hair follicle -- stem cells -- wound healing -- review; Gene therapy -- Periodicals; Protein drugs -- Periodicals; Peptide drugs -- Periodicals; Immunotherapy -- Periodicals; Drug delivery systems -- Periodicals; 615.5
• DOI: 10.1080/14712598.2019.1559290
• Languages: English
• ISSNs: 1471-2598

Abstract

ABSTRACT: Introduction : With the continued focus on in-depth investigations of hair follicle stem cells (HFSCs), the role of HFSCs in wound healing has attracted increasing attention from researchers. This review may afford meaningful implications for HFSC treatment of wounds. Areas covered : We present the properties of HFSCs, analyze the possibility of HFSCs in wound healing, and sum up the recent studies into wound repair with HFSCs. The details of HFSCs in wound healing have been discussed. The possible mechanisms of wound healing with HFSCs have been elaborated. Additionally, the factors that influence HFSCs in wound healing are also summarized. Expert opinion : Hair follicle stem cells are promising sources for wound healing. However, a further understanding of human HFSCs and the safety use of HFSCs in clinical practice still remain in relative infancy.