Bullous Skin Diseases: Classical Types of Autoimmune Diseases. (8th January 2013)

• Record Type: Journal Article
• Authors: Damoiseaux, Jan
• Other Names: Amedei Amedeo Academic Editor.; Lesinski Gregory Academic Editor.; Tursen Umit Academic Editor.
• Is Part Of: Scientifica. Volume 2013(2013)
• Publication Date: 2013-01-08
• Subjects: Life sciences -- Periodicals; Biology -- Periodicals; Medicine -- Periodicals; Biological Science Disciplines; Medicine; Biology; Life sciences; Medicine; Periodicals; Electronic journals; Periodicals; 500
• DOI: 10.1155/2013/457982
• Languages: English
• ISSNs: 2090-908X

Abstract

Abstract : The prototypic bullous skin diseases, pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid, are characterized by the blister formation in the skin and/or oral mucosa in combination with circulating and deposited autoantibodies reactive with (hemi)desmosomes. Koch's postulates, adapted for autoimmune diseases, were applied on these skin diseases. It appears that all adapted Koch's postulates are fulfilled, and, therefore, these bullous skin diseases are to be considered classical autoimmune diseases within the wide and expanding spectrum of autoimmune diseases.