An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month. Issue 10 (9th June 2014)

• Record Type: Journal Article
• Authors: Vandenplas, Yvan; De Greef, Elisabeth; Hauser, Bruno
• Other Names: Halut C author non-byline.; Robberecht MN author non-byline.; Balduck N author non-byline.; l'Homme A author non-byline.; Mohring MP author non-byline.; Carvelli T author non-byline.; Hauser B author non-byline.; Defontaine E author non-byline.; Questiau JF author non-byline.; Christens J author non-byline.; Henckens F author non-byline.; Lemmens R author non-byline.; Vercammen L author non-byline.; De Greef E author non-byline.
• Is Part Of: Archives of disease in childhood. Volume 99:Issue 10(2014)
• Page Start: 933
• Page End: 936
• Publication Date: 2014-06-09
• Subjects: Allergy -- Gastroenterology -- General Paediatrics -- Nutrition; Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/archdischild-2013-304727
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Background: Guidelines recommend extensively hydrolysed cow's milk protein formulas (eHF) in the treatment of infants diagnosed with cow's milk protein allergy (CMPA). Extensively hydrolysed rice protein infant formulas (eRHFs) have recently become available, and could offer a valid alternative. Methods: A prospective trial was performed to evaluate the clinical tolerance of a new eRHF in infants with a confirmed CMPA. Patients were followed for 1 month. Clinical tolerance of the eRHF was evaluated with a symptom-based score (SBS) and growth (weight and length) was monitored. Results: Thirty-nine infants (mean age 3.4 months, range 0.5–6 months) diagnosed with CMPA were enrolled. All infants tolerated the eRHF and experienced a normal growth. Conclusions: In accordance with current guidelines, this eRHF is tolerated by more than 90% of children with proven CMPA with a 95% CI, and is an adequate alternative to cow's milk-based eHF. Trial registration number: ClinicalTrials.gov NCT01998074 .