Systemic Lymphadenectomy Cannot Be Recommended for Low-Risk Corpus Cancer. (4th February 2010)

• Record Type: Journal Article
• Authors: Hidaka, Takao; Nakashima, Akitoshi; Shima, Tomoko; Hasegawa, Toru; Saito, Shigeru
• Other Names: Hernandez Enrique Academic Editor.
• Is Part Of: Obstetrics and gynecology international. Volume 2010(2010)
• Publication Date: 2010-02-04
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1005
• DOI: 10.1155/2010/490219
• Languages: English
• ISSNs: 1687-9589

Abstract

Abstract : Objective . The objective of this study is to ascertain whether omission of lymphadenectomy could be possible when uterine corpus cancer is considered low-risk based on intraoperative pathologic indicators. Patient and Methods . Between 1998 and 2007, a total of 83 patients with low risk corpus cancer (endometrioid type, grade 1 or 2, myometrial invasion ≦ 50%, and no intraoperative evidence of macroscopic extrauterine spread, including pelvic and paraaortic lymph node swelling and adnexal metastasis) underwent the total abdominal hysterectomy and bilateral salpingo-oophorectomy without lymphadenectomy. A retrospective review of the medical records was performed, and the disease-free survival (DFS), overall survival (OS), peri- and postoperative morbidities and complications were evaluated. Results . The 5-year DFS rates and the 5-year OS rates were 97.6% and 98.8%, respectively. No patient presented postoperative leg lymphedema and deep venous thrombosis. Conclusion . Omission of lymphadenectomy did not worsen the DFS or OS. The present findings suggest that systemic lymphadenectomy could be omitted in low-risk endometrial carcinoma.