A Proposal for Six Sigma Integration for Large-Scale Production of Penicillin G and Subsequent Conversion to 6-APA. (24th February 2014)

• Record Type: Journal Article
• Authors: Nandi, Anirban; Pan, Sharadwata; Potumarthi, Ravichandra; Danquah, Michael K.; Sarethy, Indira P.
• Other Names: Doddapaneni Kiran Kumar Academic Editor.
• Is Part Of: Journal of analytical methods in chemistry. Volume 2014(2014)
• Publication Date: 2014-02-24
• Subjects: Chemistry, Analytic -- Periodicals; Chemistry, Analytic -- Technique -- Periodicals; 543.05
• DOI: 10.1155/2014/413616
• Languages: English
• ISSNs: 2090-8865

Abstract

Abstract : Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D). In the current study, we have reviewed and proposed a process for a probable integration of Six Sigma methodology to large-scale production of Penicillin G and its subsequent conversion to 6-aminopenicillanic acid (6-APA). It is anticipated that the important aspects of quality control and quality assurance will highly benefit from the integration of Six Sigma methodology in mass production of Penicillin G and/or its conversion to 6-APA.