P026 RELATIONS BETWEEN PHYSICAL ACTIVITY, DIET, AND BODY COMPOSITION IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASE. (7th February 2019)

• Record Type: Journal Article
• Authors: Barnes, Margaux J; Nagaraj, Pooja K; Knight, Taylor J; Jester, Traci W
• Is Part Of: Inflammatory bowel diseases. Volume 25(2019)Supplement 1
• Page Start: S13
• Page End: S13
• Publication Date: 2019-02-07
• Subjects: Inflammatory bowel diseases -- Periodicals; Colitis, Ulcerative -- Periodicals; Crohn Disease -- Periodicals; Inflammatory Bowel Diseases -- Periodicals; 616.344
• DOI: 10.1093/ibd/izy393.030
• Languages: English
• ISSNs: 1078-0998

Abstract

Abstract: Background: The presence of lean mass (LM) deficits in pediatric patients with IBD is well established, and these deficits persist despite achievement of remission and restoration of body mass. LM deficits are associated with negative health outcomes including decreased physical function, metabolic dysregulation, increased risk of infection, and reduction of bone mass. These deficits are multifactorial though largely explained by chronic malnutrition due to enteric nutrient losses, inadequate dietary intake, malabsorption of nutrients, and increased energy needs. In addition to malnutrition, physical activity (PA) may also play a role in the low LM and myopenia noted in youth with IBD. Unfortunately, PA and dietary intake have been relatively understudied in this population. As such, the present cross-sectional pilot study aims to describe relations between PA, dietary intake, and body composition in a sample of pediatric patients with IBD compared to healthy peers. Methods: 87 patients aged 8-17 years completed the study (31 Crohn's Disease (CD), 23 Ulcerative Colitis (UC), and 31 Healthy Controls (HC) completed the study protocol. Assessment measures included: PA (Godin Leisure Time Exercise Questionnaire), 4-Day Food Records, Body Composition and Bone Density (Dual-energy X-ray Absorptiometry; DXA). Medical record reviews were conducted for IBD patients only. Analyses included one-way ANOVAs to evaluate differences between study groups and two-tailed Pearson correlations to evaluate relations between variables of interest across groups. Results: Healthy controls had significantly greater moderate to vigorous physical activity compared to both IBD groups and were significantly younger than and consumed a higher percentage of calories from fat compared to youth with UC. Youth with UC consumed a significantly higher percentage of calories from carbohydrates compared to HC but not CD participants. No other statistically significant differences were found based on the study group. Correlational analyses (N = 87) revealed that being male (r =.-.30), older age (r =.72), higher total energy intake (r =.22), a higher percentage of calories from protein (r =.37), and higher BMI z-score (r =.51) were associated with higher total body LM. While physical activity was not related to LM, it is possible that differences would be noted if activities were coded as resistance versus aerobic exercise as these have been shown to have differential effects on LM. Conclusions: Understanding health behaviors associated with the development of LM, including PA and dietary intake, are key to improving growth and development outcomes in pediatric patients with IBD. The present study suggests the need for further research into PA and macronutrient intake as a means of promoting short and long-term health and well-being for pediatric patients with IBD.