Antifouling potentials of eight deep-sea-derived fungi from the South China Sea. (1st April 2014)

• Record Type: Journal Article
• Authors: Zhang, Xiao-Yong; Xu, Xin-Ya; Peng, Jiang; Ma, Chun-Feng; Nong, Xu-Hua; Bao, Jie; Zhang, Guang-Zhao; Qi, Shu-Hua
• Is Part Of: Journal of industrial microbiology & biotechnology. Volume 41:Number 4(2014)
• Page Start: 741
• Page End: 748
• Publication Date: 2014-04-01
• Subjects: Deep-sea-derived fungi -- Antibacterial -- Antifouling -- Aspergillus westerdijkiae -- Alkaloids; Industrial microbiology -- Periodicals; 660.62
• DOI: 10.1007/s10295-014-1412-9
• Languages: English
• ISSNs: 1367-5435

Abstract

Abstract: Marine-derived microbial secondary metabolites are promising potential sources of nontoxic antifouling agents. The search for environmentally friendly and low-toxic antifouling components guided us to investigate the antifouling potentials of eight novel fungal isolates from deep-sea sediments of the South China Sea. Sixteen crude ethyl acetate extracts of the eight fungal isolates showed distinct antibacterial activity against three marine bacteria ( Loktanella hongkongensis UST950701–009, Micrococcus luteus UST950701–006 and Pseudoalteromonas piscida UST010620–005), or significant antilarval activity against larval settlement of bryozoan Bugula neritina . Furthermore, the extract of Aspergillus westerdijkiae DFFSCS013 displayed strong antifouling activity in a field trial lasting 4 months. By further bioassay-guided isolation, five antifouling alkaloids including brevianamide F, circumdatin F and L, notoamide C, and 5-chlorosclerotiamide were isolated from the extract of A. westerdijkiae DFFSCS013. This is the first report about the antifouling potentials of metabolites of the deep-sea-derived fungi from the South China Sea, and the first stage towards the development of non- or low-toxic antifouling agents from deep-sea-derived fungi.