Co(II) and Cd(II) Complexes Derived from Heterocyclic Schiff-Bases: Synthesis, Structural Characterisation, and Biological Activity. (19th August 2013)

• Record Type: Journal Article
• Authors: Ahmed, Riyadh M.; Yousif, Enaam I.; Al-Jeboori, Mohamad J.
• Other Names: Matesanz A. I. Academic Editor.; Souldozi A. Academic Editor.
• Is Part Of: TheScientificWorldjournal. Volume 2013(2013)
• Publication Date: 2013-08-19
• Subjects: Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1155/2013/754868
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : New monomeric cobalt and cadmium complexes with Schiff-bases, namely, N ′-[( E )-(3-hydroxy-4-methoxyphenyl)methylidene]furan-2-carbohydrazide (L 1 ) and N ′-[( E )-(3-hydroxy-4-methoxyphenyl)methylidene]thiophene-2-carbohydrazide (L 2 ) are reported. Schiff-base ligands L 1 and L 2 were derived from condensation of 3-hydroxy-4-methoxybenzaldehyde (iso-vanillin) with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide, respectively. Complexes of the general formula [M(L)2 ]Cl2 (where M = Co(II) or Cd(II), L = L 1 or L 2 ) have been obtained from the reaction of the corresponding metal chloride with the ligands. The ligands and their metal complexes were characterised by spectroscopic methods (FTIR, UV-Vis, 1 H, and 13 C NMR spectra), elemental analysis, metal content, magnetic measurement, and conductance. These studies revealed the formation of four-coordinate complexes in which the geometry about metal ion is tetrahedral. Biological activity of the ligands and their metal complexes against gram positive bacterial strain Bacillus (G+) and gram negative bacteria Pseudomonas (G−) revealed that the metal complexes become less resistive to the microbial activities as compared to the free ligands.