Clinical characteristics associated with COVID-19 severity in California. Issue 1 (16th April 2020)

• Record Type: Journal Article
• Authors: Rubin, Samuel J. S.; Falkson, Samuel R.; Degner, Nicholas R.; Blish, Catherine
• Is Part Of: Journal of clinical and translational science. Volume 5:Issue 1(2021)
• Publication Date: 2020-04-16
• Subjects: COVID-19, -- SARS-CoV-2, -- oxygen saturation, -- hypertension, -- acute respiratory distress syndrome (ARDS), -- severe acute respiratory syndrome (SARS); Clinical medicine -- Research -- Periodicals; Medicine, Experimental -- Periodicals; Human experimentation in medicine -- Periodicals; 616.027
• DOI: 10.1017/cts.2020.40
• Languages: English
• ISSNs: 2059-8661

Abstract

Abstract: Given the rapidly progressing coronavirus disease 2019 (COVID-19) pandemic, this report on a US cohort of 54 COVID-19 patients from Stanford Hospital and data regarding risk factors for severe disease obtained at initial clinical presentation is highly important and immediately clinically relevant. We identified low presenting oxygen saturation as predictive of severe disease outcomes, such as diagnosis of pneumonia, acute respiratory distress syndrome, and admission to the intensive care unit, and also replicated data from China suggesting an association between hypertension and disease severity. Clinicians will benefit by tools to rapidly risk stratify patients at presentation by likelihood of progression to severe disease.