Extraovarian juvenile granulosa cell tumor in a prepubertal child: novel location of a rare tumor. (16th November 2020)

• Record Type: Journal Article
• Authors: User, İdil Rana; Ardıçlı, Burak; Yalçın, Bilgehan; Orhan, Diclehan; Müngen, Eren; Özcan, Nursun; Ekinci, Saniye
• Is Part Of: Pediatric hematology and oncology. Volume 38:Number 3(2021)
• Page Start: 272
• Page End: 277
• Publication Date: 2020-11-16
• Subjects: Child -- extragonadal -- Juvenile granulosa cell tumor; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Hematologic Diseases -- Child; Hematologic Diseases -- Infant; Neoplasms -- Child; 618.9215
• DOI: 10.1080/08880018.2020.1850953
• Languages: English
• ISSNs: 0888-0018

Abstract

Abstract: Juvenile granulosa cell tumor (JGCT) is the most common type of sex cord stromal tumor arising from gonadal structures of children and young adults. We present a 3.5-year-old girl with JGCT located in retroperitoneum without ovarian involvement. Extragonadal occurrences of other sex cord stromal tumors have been rarely reported, but this is the first case of JGCT in an extragonadal location. We speculate the possible underlying mechanism of sex cord stromal tumor formation in extragonadal locations. Furthermore, clinical presentation, differential diagnosis and management of this tumor in childhood are discussed.