The role of trehalose in the global spread of epidemic Clostridium difficile. (4th March 2019)

• Record Type: Journal Article
• Authors: Collins, James; Danhof, Heather; Britton, Robert A.
• Is Part Of: Gut microbes. Volume 10:Isuse 2(2019)
• Page Start: 204
• Page End: 209
• Publication Date: 2019-03-04
• Subjects: Clostridium difficile -- trehalose -- RT017 -- ribotype 017 -- enteric pathogen; Gastrointestinal system -- Microbiology -- Periodicals; Microbiology -- Periodicals; Intestine, Small -- Periodicals; 616.3
• DOI: 10.1080/19490976.2018.1491266
• Languages: English
• ISSNs: 1949-0984

Abstract

ABSTRACT: In a recent study, we reported on two distantly related, epidemic lineages of Clostridium difficile that have acquired independent mechanisms to metabolize low concentrations of trehalose. Here we provide further comment and evidence that a third epidemic lineage common in Asia and Europe, ribotype 017, has evolved this ability.