Detection of Anti-Toxoplasma gondii IgG and IgM Antibodies and Associated Risk Factors during Pregnancy in Southwest Iran. (27th May 2021)

• Record Type: Journal Article
• Authors: Soltani, Shahrzad; Ghaffari, Ali Dalir; Kahvaz, Mehdi Sagha; Sabaghan, Mohamad; Pashmforosh, Marzieh; Foroutan, Masoud
• Other Names: Larsen Bryan Academic Editor.
• Is Part Of: Infectious diseases in obstetrics and gynecology. Volume 2021(2021)
• Publication Date: 2021-05-27
• Subjects: Generative organs, Female -- Infections -- Periodicals; Communicable diseases in pregnancy -- Periodicals; 618.142005
• DOI: 10.1155/2021/5547667
• Languages: English
• ISSNs: 1064-7449

Abstract

Abstract : Background . This research was aimed at evaluating the seroprevalence of acute and chronic Toxoplasma gondii ( T. gondii ) infection in pregnant women and related risk factors in southwest Iran. Methods . In this cross-sectional study, eighty-eight pregnant women were included from October 2019 to December 2019. The presence of anti- T. gondii IgM and IgG antibodies was measured using the enzyme-linked immunosorbent assay (ELISA). In addition, a questionnaire consisting of demographic information was completed for each subject. Results . The overall seroprevalence of T. gondii infection was estimated to be 34.09% (30/88). Of these, 1 (1.13%) and 29 (32.95%) samples were found positive for IgM and IgG, respectively. Regarding the risk factors, the consumption of raw/undercooked meat (P value = 0.007) and history of abortion (P value = 0.017) were significantly associated with IgG seroprevalence in pregnant women. Conclusion . The results showed that the pregnant women of southwest Iran might be moderately exposed to T. gondii . Since the risk of acute T. gondii infection in this susceptible group is very important, regular screening tests to diagnose the infection are recommended before pregnancy.