The Possible Clinical Predictors of Fatigue in Parkinson's Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project. (5th December 2011)

• Record Type: Journal Article
• Authors: Metta, Vinod; Logishetty, Kartik; Martinez-Martin, P.; Gage, Heather M.; Schartau, P. E. S.; Kaluarachchi, T. K.; Martin, Anne; Odin, Per; Barone, P.; Stocchi, Fabrizio; Antonini, A.; Chaudhuri, K. Ray
• Other Names: Strafella Antonio Academic Editor.
• Is Part Of: Parkinson's disease. Volume 2011(2011)
• Publication Date: 2011-12-05
• Subjects: Parkinson's disease -- Periodicals; Parkinson's disease -- Treatment -- Periodicals; 616.833005
• DOI: 10.4061/2011/125271
• Languages: English
• ISSNs: 2090-8083

Abstract

Abstract : Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.