Extracellular RNAs: development as biomarkers of human disease. Issue 1 (28th August 2015)

• Record Type: Journal Article
• Authors: Quinn, Joseph F.; Patel, Tushar; Wong, David; Das, Saumya; Freedman, Jane E.; Laurent, Louise C.; Carter, Bob S.; Hochberg, Fred; Keuren‐Jensen, Kendall Van; Huentelman, Matt; Spetzler, Robert; S. Kalani, M. Yashar; Arango, Jorge; Adelson, P. David; Weiner, Howard L.; Gandhi, Roopali; Goilav, Beatrice; Putterman, Chaim; Saugstad, Julie A.
• Is Part Of: Journal of extracellular vesicles. Volume 4:Issue 1(2015)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2015-08-28
• Subjects: ERCC -- exRNA -- extracellular RNA -- biomarkers; Cells -- Mechanical properties -- Periodicals; Transport Vesicles; Cells -- Mechanical properties; Periodicals; Fulltext; Internet Resources; Periodicals; Electronic journals; Periodicals; 571.63
• DOI: 10.3402/jev.v4.27495
• Languages: English
• ISSNs: 2001-3078

Abstract

Abstract : Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.