Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury. (10th May 2021)

• Record Type: Journal Article
• Authors: Pham, Phuong Chi; Konanur Ventakaram, Raghu; Pham, Jimmy; Sidhu, Harpreet; Bader, Nada; Pham, Phuong Mai; Pham, Phuong Thu
• Other Names: Exadaktylos Aristomenis K. Academic Editor.
• Is Part Of: Case reports in medicine. Volume 2021(2021)
• Publication Date: 2021-05-10
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Case Reports; Periodicals; 610
• DOI: 10.1155/2021/9962624
• Languages: English
• ISSNs: 1687-9627

Abstract

Abstract : Hyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniques. We herein present a case of a young pregnant woman who presented with mild acute kidney injury (AKI), invasive mucormycosis receiving liposomal amphotericin, and hyperphosphatemia out of proportion to the degree of kidney injury. While the patient was given routine phosphate-binding agent by her primary care team for presumed AKI-associated hyperphosphatemia, a full investigation by the renal consulting team for contributing factors other than kidney injury revealed that she actually had pseudohyperphosphatemia associated with the use of liposomal amphotericin. Erroneous treatment of pseudohyperphosphatemia may have been detrimental to this pregnant patient. A literature review for conditions associated with pseudohyperphosphatemia other than the use of liposomal amphotericin will be discussed.