A highly sensitive fluorescent probe for hydrazine detection: synthesis, characterisation and application in living cells. Issue 8 (21st June 2021)

• Record Type: Journal Article
• Authors: Ye, Hui; Chen, Li; Wang, Xinxian; Lu, Dingqiang
• Is Part Of: International journal of environmental analytical chemistry. Volume 101:Issue 8(2021)
• Page Start: 1086
• Page End: 1098
• Publication Date: 2021-06-21
• Subjects: Probe -- Hydrazine -- Imidazo [15-a]pyridine -- Cellular imaging; Ecology -- Periodicals; Chemistry, Analytic -- Periodicals; Environmental chemistry -- Periodicals; Pollution -- Periodicals; 577.14
• DOI: 10.1080/03067319.2019.1676422
• Languages: English
• ISSNs: 0306-7319

Abstract

ABSTRACT: A new fluorescent probe HSL-AI derived from imidazo [1, 5- a ]pyridine was synthesised for the detection of hydrazine (N2 H4 ) based on excited-state intramolecular proton transfer (ESIPT). HSL-AI was designed using acetyl group as the recognition site and exhibited high selectivity towards N2 H4 with a low limit of detection (2.56 ppb). Moreover, HSL-AI was successfully applied to detect N2 H4 in living cells.