Chemotaxonomy and cytotoxicity of the liverwort Porella Viridissima. Issue 12 (31st May 2021)

• Record Type: Journal Article
• Authors: Métoyer, Benjamin; Lebouvier, Nicolas; Hnawia, Edouard; Thouvenot, Louis; Wang, Fengrui; Harinantenaina Rakotondraibe, Liva; Raharivelomanana, Phila; Asakawa, Yoshinori; Nour, Mohammed
• Is Part Of: Natural product research. Volume 35:Issue 12(2021)
• Page Start: 2099
• Page End: 2102
• Publication Date: 2021-05-31
• Subjects: Liverwort -- Porella viridissima -- chemotype -- pinguisane -- sacculatane -- ovarian cancer; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1655022
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesquiterpenes are reported for the first time in liverwort. P. viridissima was found to belong to the chemotype III (pinguisane/sacculatane) and shared chemical similarities with P. navicularis . Perrotettianal A was isolated and has shown strong cytotoxicity against ovarian cancer. GRAPHICAL ABSTRACT: