Inhibitory Effects and Caspase 3 Activation Activity of Natural Compounds from Anemarrhena Asphodeloides (Bunge) Rhizomes in Vietnam. Issue 3 (4th May 2021)

• Record Type: Journal Article
• Authors: Truong, Mai Xuan; Huong, Mai Lan; Anh, Nguyen Thi Quynh; Shen, Sida; Khang, Pham Van
• Is Part Of: Journal of biologically active products from nature. Volume 11:Issue 3(2021)
• Page Start: 223
• Page End: 227
• Publication Date: 2021-05-04
• Subjects: Anemarrhena asphodeloides -- NMR -- MS -- Natural product -- Vietnam; Natural products -- Periodicals; Biological products -- Periodicals; 660.6
• DOI: 10.1080/22311866.2021.1919207
• Languages: English
• ISSNs: 2231-1866

Abstract

Abstract: Three compounds were identified from the ethanolic extract of Anemarrhena asphodeloides Bunge (A. asphodeloides ) plant using silica gel chromatography. Their structures were confirmed by NMR and MS data analysis. The inhibitory activities against the MCF7 cancer cell line were evaluated and study the caspase 3 activation activity. Compound 3 exhibited good inhibitory activity and caspase 3 activation activity on the MCF7 cell line.