Enhanced non-enzymatic glucose sensing based on porous ZIF-67 hollow nanoprisms. (19th May 2021)

• Record Type: Journal Article
• Authors: Chen, Qiwen; Chu, Dandan; Yan, Li; Lai, Haichen; Chu, Xue-Qiang; Ge, Danhua; Chen, Xiaojun
• Is Part Of: New journal of chemistry. Volume 45:Number 22(2021)
• Page Start: 10031
• Page End: 10039
• Publication Date: 2021-05-19
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d1nj01138c
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : Porous ZIF-67 hollow nanoprisms based non-enzymatic glucose sensor was successfully prepared using Co5 (OH)2 (OAc)8 ·2H2 O as a precursor by a diffusion-controlled strategy, which exhibited wide linear range and high sensitivity. Abstract : Metal–organic frameworks (MOFs) as porous materials have significantly improved catalytic properties because of their rich active sites and large surface area. Herein, we develop a facile and efficient diffusion-controlled strategy to prepare ZIF-67 hollow nanoprisms (ZIF-67 HNPs) for a non-enzymatic glucose sensor. The interparticle pores of the hollow structure can afford fast diffusion pathway for guest molecules to move in and out of the MOF crystals. Such nanostructured MOF-based sensors exhibit good electrocatalytic activity towards glucose oxidation in an alkaline solution with a high sensitivity of 445.7 μA mM −1 cm −2, a low detection limit of 0.96 μM (S/N = 3) and a upper limit of 42.1 mM, and can be used to directly determine blood glucose. Moreover, it achieves well-pleasing results in the non-enzymatic analysis of glucose in real human blood serum samples. In addition, the as-prepared sensor also displays satisfactory reproducibility, selectivity and long-term storage stability. This study focuses on a facile strategy to design the in situ growth of hollow MOF nanomaterials as efficient and stable electrocatalysts, shedding light on the development of non-enzymatic sensors for monitoring glucose with transition metal-based hollow MOF catalysts.