Yield of Severe Acute Respiratory Syndrome Coronavirus 2 Lower Respiratory Tract Testing After a Negative Nasopharyngeal Test Among Hospitalized Persons Under Investigation for Coronavirus Disease 2019. (19th May 2021)

• Record Type: Journal Article
• Authors: Egbuonu, Kenechukwu; Hyle, Emily P; Hurtado, Rocio M; Alba, George A; Zachary, Kimon C; Branda, John A; Hibbert, Kathryn A; Hooper, David C; Shenoy, Erica S; Turbett, Sarah E; Dugdale, Caitlin M
• Is Part Of: Open forum infectious diseases. Volume 8:Number 6(2021)
• Publication Date: 2021-05-19
• Subjects: COVID-19 testing -- coronavirus -- lower respiratory tract; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofab257
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Among hospitalized persons under investigation for coronavirus disease 2019 (COVID-19), more repeated severe acute respiratory syndrome coronavirus 2 nucleic acid amplification tests (NAATs) after a negative NAAT were positive from lower than from upper respiratory tract specimens (1.9% vs 1.0%, P = .033). Lower respiratory testing should be prioritized among patients displaying respiratory symptoms with moderate-to-high suspicion for COVID-19 after 1 negative upper respiratory NAAT.