Infrared microspectroscopic imaging as a probing tool to fast distinguish chemical compositions in calcified deposits of prostatic calculi and calcific tendonitis. Issue 5 (2011)

• Record Type: Journal Article
• Authors: Lin, Shan-Yang; Wu, Tieh-Kang; Chiou, Hong-Jen; Hsu, Ted Hueih-Shing; Lin, Chih-Cheng
• Is Part Of: Spectroscopy. Volume 25:Issue 5(2011)
• Page Start: 207
• Page End: 216
• Publication Date: 2011
• Subjects: FT-IR mapping -- second-derivative analysis -- calcified tissue -- component
• DOI: 10.3233/SPE-2011-0510
• Languages: English
• ISSNs: 0712-4813

Abstract

Abstract : The specificity and homogeneity of the real compositional components within the calcified deposits of prostatic calculi and calcific tendonitis were investigated using Fourier transform infrared (FT-IR) microspectroscopy with or without automatic imaging system. The second-derivative analysis was also applied to differentiate the overlapping components of individual spectra for the calcified samples. The FT-IR microscopic imaging results of present study indicate that the complicated components such as protein, type B or type A carbonated apatite, brushite and calcium oxalate monohydrate were contained in the calcified tissue of prostatic tissue, but the protein, type A and type B carbonated apatites were mainly included in the calcific tendonitis. However, the traditional manually single-point FT-IR spectral result only reveals a little component contained in the calcified tissues, leading to an inaccurate diagnose of the complicated components in the calcified mixture.